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去分化型腹膜后大脂肪肉瘤与腹腔镜治疗:可行且安全吗?首例文献病例报告。

Dedifferentiated retroperitoneal large liposarcoma and laparoscopic treatment: Is it possible and safe? The first literature case report.

作者信息

Agrusa Antonino, Di Buono Giuseppe, Buscemi Salvatore, Randisi Brenda, Gulotta Leonardo, Sorce Vincenzo, Badalamenti Giuseppe, Albano Domenico, Galia Massimo, Romano Giorgio, Gulotta Gaspare

机构信息

Department of Surgical, Oncological and Oral Sciences, Section of General and Urgent Surgery, University of Palermo, Italy.

Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, Italy.

出版信息

Int J Surg Case Rep. 2019;57:113-117. doi: 10.1016/j.ijscr.2019.03.023. Epub 2019 Mar 26.

Abstract

INTRODUCTION

Soft tissue sarcomas are rare neoplasms often characterized by local invasiveness and distant metastasis with poor prognosis for affected patients. Among the most frequent sarcomas we find well-differentiated and dedifferentiated liposarcomas characterized by a better survival compared to the other histological types. When it is possible the only curative treatment for these neoplasms is surgical resection.

CASE REPORT

We report a case of a 62-year-old caucasian woman with CT abdominal scan that demonstrated a voluminous solid oval mass in the left perirenal space with dislocation of the kidney and in continuity with the anterior renal fascia. After a percutaneous CT-guided biopsy of the mass the histopathological diagnosis was a dedifferentiated retroperitoneal liposarcoma. We performed a laparoscopic surgical resection of the retroperitoneal mass in block with kidney and left adrenal gland.

DISCUSSION

When possible, surgical resection with adequate margins represents the only curative therapeutic option for this pathology. Only a few papers are available in literature which take into consideration the possibility of laparoscopic approach for retroperitoneal masses with better vision of surgical field, reduction of post-operative pain and better cosmesis.

CONCLUSION

A retroperitoneal mass represents a serious diagnostic challenge. The choice of the best surgical procedure can benefit to the patient prognosis. To our opinion laparoscopy can be a safe and successful treatment and it can represent a valid alternative to open surgery. However, we have no randomized controlled trials that compare laparoscopic versus open resection for retroperitoneal liposarcomas.

摘要

引言

软组织肉瘤是罕见的肿瘤,通常具有局部侵袭性和远处转移的特点,患病患者预后较差。在最常见的肉瘤中,我们发现高分化和去分化脂肪肉瘤与其他组织学类型相比,生存期更长。如果可能的话,这些肿瘤唯一的治愈性治疗方法是手术切除。

病例报告

我们报告一例62岁的白种女性,腹部CT扫描显示左肾周间隙有一个巨大的实性椭圆形肿块,肾脏移位,与肾前筋膜相连。在对该肿块进行CT引导下经皮活检后,组织病理学诊断为去分化腹膜后脂肪肉瘤。我们进行了腹腔镜手术,整块切除腹膜后肿块以及肾脏和左肾上腺。

讨论

如果可能,进行具有足够切缘的手术切除是这种病理状况唯一的治愈性治疗选择。文献中仅有少数几篇论文考虑了采用腹腔镜方法处理腹膜后肿块的可能性,这种方法具有手术视野更好、术后疼痛减轻和美容效果更佳的优点。

结论

腹膜后肿块是一个严峻的诊断挑战。选择最佳的手术方式对患者的预后有益。我们认为腹腔镜手术可以是一种安全且成功的治疗方法,它可以成为开放手术的有效替代方案。然而,我们没有随机对照试验来比较腹腔镜手术与开放手术治疗腹膜后脂肪肉瘤的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edda/6446056/07397dfd5712/gr1.jpg

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