Di Buono Giuseppe, Buscemi Salvatore, Maienza Elisa, Bonventre Giulia, Romano Giorgio, Agrusa Antonino
Department of Surgical, Oncological and Oral Sciences, Section of General and Urgent Surgery, University of Palermo, Italy.
Int J Surg Case Rep. 2020;77S(Suppl):S8-S12. doi: 10.1016/j.ijscr.2020.10.001. Epub 2020 Oct 16.
Gastrosplenic fistula is a rare disease involving stomach and spleen that can lead to dangerous complications like massive gastrointestinal bleeding. Diffuse large B-cell lymphoma (DLBC) is the principal pathological cause of gastrosplenic fistula.
We report a case of A 76-year-old caucasian woman came to the emergency room with fever for two week and gravative pain in left upper quadrant of the abdomen. CT scan of thorax and abdomen demonstrated an inhomogeneous hypodense large lymphomatous mass (10 × 6 cm) of upper pole of the spleen deformating medial profile and infiltrating gastric fundus and left diaphragm. with the diagnosis of complex gastro-splenic-diaphragmatic fistula we performed an en-block resection using a 3D laparoscopic vision system.
Gastrosplenic fistula is a rare complication of several clinical conditions. Among the different causes diffuse large B-cell lymphoma is the most frequent although diffuse histiocytic lymphoma, Hodgkin's lymphoma and extranodal NK/T-cell lymphoma are also described. After a literature review we found less then 30 cases of gastrosplenic fistula secondary to lymphoma. In our case report we do the first description of three-organs fistula envolvement, stomach, spleen and diaphragmatic dome, managed with 3D laparoscopic approach.
Gastrosplenic fistula can represent a fatal evolution of splenic or gastric lymphoma independently from chemotherapy treatment. The diagnosis of this condition is very difficult and related to its rarity. To our opinion, laparoscopy represents a valid and safe alternative to open surgery in management of these patients.
胃脾瘘是一种涉及胃和脾脏的罕见疾病,可导致大量胃肠道出血等危险并发症。弥漫性大B细胞淋巴瘤(DLBC)是胃脾瘘的主要病理原因。
我们报告一例76岁的白种女性患者,因发热两周和左上腹隐痛前来急诊室。胸部和腹部CT扫描显示脾脏上极有一个不均匀的低密度大淋巴瘤肿块(10×6 cm),使内侧轮廓变形并侵犯胃底和左膈。诊断为复杂的胃脾膈瘘后,我们使用3D腹腔镜视觉系统进行了整块切除。
胃脾瘘是几种临床情况的罕见并发症。在不同病因中,弥漫性大B细胞淋巴瘤最为常见,不过也有弥漫性组织细胞淋巴瘤、霍奇金淋巴瘤和结外NK/T细胞淋巴瘤的相关描述。经文献回顾,我们发现继发于淋巴瘤的胃脾瘘病例少于30例。在我们的病例报告中,首次描述了采用3D腹腔镜方法处理的胃、脾和膈顶三器官瘘受累情况。
胃脾瘘可能代表脾脏或胃淋巴瘤的致命进展,与化疗治疗无关。这种疾病的诊断非常困难,因其罕见。我们认为,在这些患者的管理中,腹腔镜检查是开放手术的一种有效且安全的替代方法。