糖尿病患者的腓肠神经氧分压
Sural nerve oxygen tension in diabetes.
作者信息
Newrick P G, Wilson A J, Jakubowski J, Boulton A J, Ward J D
出版信息
Br Med J (Clin Res Ed). 1986 Oct 25;293(6554):1053-4. doi: 10.1136/bmj.293.6554.1053.
Abstract
Peripheral nerve oxygen tensions were assessed in vivo by using microelectrodes to measure endoneurial oxygen tension in exposed sural nerve. In 11 diabetic patients with chronic sensorimotor neuropathy the mean endoneurial oxygen tension was 39.7 (SD 10.2) mm Hg. In all but one patient compared with none of four non-neuropathic subjects the mean nerve oxygen tensions were below dorsal foot vein values. This unphysiological state may have a role in the aetiology of diabetic neuropathy.
摘要
通过使用微电极测量暴露的腓肠神经的神经内膜氧张力，在体内评估周围神经的氧张力。在11例患有慢性感觉运动性神经病变的糖尿病患者中，神经内膜平均氧张力为39.7（标准差10.2）毫米汞柱。除1例患者外，所有患者的平均神经氧张力均低于4例非神经病变受试者中的任何一人，且低于足背静脉值。这种非生理状态可能在糖尿病神经病变的病因学中起作用。
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