Williams R, Nussey S, Humphry R, Thompson G
Br Med J (Clin Res Ed). 1986 Nov 1;293(6555):1140-2. doi: 10.1136/bmj.293.6555.1140.
Non-mydriatic retinal photography with later interpretation of the photographs was assessed as a screening method for the detection of diabetic retinopathy; when compared with an ophthalmologist's clinical assessment in a random group of 62 diabetic patients it was accurate (false negative 6.8%, false positive 2%) and sensitive (sensitivity 96%, specificity 98%). The assessment of further management required based on analysis of the photographs was 96.5% in agreement with the further management suggested by the ophthalmologist after direct clinical assessment of the patient. If this technique were used to screen patients in a typical diabetic clinic the predicted positive accuracy rate would be 84% and the predicted negative accuracy rate 99.5%.
对免散瞳视网膜摄影术及后续照片解读作为糖尿病视网膜病变检测筛查方法进行了评估;在一组62名糖尿病患者的随机分组中,将其与眼科医生的临床评估相比较,结果显示该方法准确(假阴性率6.8%,假阳性率2%)且灵敏(灵敏度96%,特异度98%)。基于照片分析对进一步治疗需求的评估与眼科医生在对患者进行直接临床评估后建议的进一步治疗的符合率为96.5%。如果将该技术用于典型糖尿病诊所的患者筛查,预测阳性准确率将为84%,预测阴性准确率将为99.5%。