Shanghai Key Laboratory of Functional Materials Chemistry, School of Chemistry and Molecular Engineering , East China University of Science and Technology , Shanghai 200237 , China.
Department of Pharmacy , Anhui Medical College , Hefei 230601 , China.
ACS Appl Mater Interfaces. 2019 May 1;11(17):15998-16005. doi: 10.1021/acsami.9b01123. Epub 2019 Apr 17.
Lanthanide coordination polymers have been recently regarded as attractive sensing materials because of their selectivity, high sensitivity, and rapid response ability. In this research, the multiporous terbium phosphonate coordination polymer microspheres (TbP-CPs) were prepared as a novel fluorescent probe, which showed a fluorescence turn-on response capability for the detection of the trace anthrax biomarker dipicolinate acid (DPA). The morphology and chemical composition of as-prepared TbP-CPs were characterized in detail. The TbP-CPs have the vegetable-flower-like structure and microporous surface. In addition, the as-prepared TbP-CPs not only possess the merits of convenience and simple preparation with high yield but also have the excellent characters as fluorescent probes, such as high stability, good selectivity, and rapid detection ability within 30 s. This proposed sensor could detect DPA with a linear relationship in concentrations ranging from 0 to 8.0 μM and a high detection sensitivity of 5.0 nM. Furthermore, the successful applications of DPA detection in urine and bovine serum were demonstrated. As a result, the recovery ranged from 93.93-101.6%, and the relative standard deviations (RSD) were less than 5%.
镧系配位聚合物由于其选择性、高灵敏度和快速响应能力，最近被认为是有吸引力的传感材料。在这项研究中，制备了多孔的三价磷酸根配位聚合物微球（TbP-CPs）作为一种新型荧光探针，该探针对炭疽生物标志物吡哆醛酸（DPA）的检测表现出荧光开启响应能力。详细地对所制备的 TbP-CPs 的形貌和化学组成进行了表征。TbP-CPs 具有类菜花状结构和微孔表面。此外，所制备的 TbP-CPs 不仅具有产率高、方便、简单制备的优点，而且还具有荧光探针的优良特性，如高稳定性、良好的选择性和在 30 秒内快速检测的能力。该传感器可在 0 至 8.0 μM 的浓度范围内检测 DPA，检测灵敏度高，为 5.0 nM。此外，还证明了该传感器在尿液和牛血清中 DPA 检测的成功应用。结果表明，回收率在 93.93-101.6%之间，相对标准偏差（RSD）小于 5%。
