Shahmanesh M, Thin R N
Eur J Epidemiol. 1986 Mar;2(1):48-51. doi: 10.1007/BF00152718.
Following the isolation of the first penicillinase-producing gonococcus in 1976 the number of such isolates rose rapidly in the United Kingdom until 1982. There was a smaller increase in 1983. At St. Thomas' Hospital, the largest clinic serving the population of South London, there was a parallel rise with stabilisation from 1982 to 1984. While for some years relatively more infections diagnosed at St Thomas' Hospital appeared to originate abroad than in the country as a whole, this proportion has gradually declined to approximately the national figure. With a gradual decline in the total numbers of gonococcal infections in the United Kingdom the proportion of infections by PPNG has continued to rise. It is important to monitor this closely, to review therapy recommendations where indicated and to maintain a vigilant watch for local epidemics.
1976年分离出首例产青霉素酶淋球菌后，此类菌株的数量在英国迅速上升，直至1982年。1983年增幅较小。在为伦敦南部人群服务的最大诊所圣托马斯医院，1982年至1984年出现了类似的上升并趋于稳定。虽然多年来在圣托马斯医院诊断出的感染病例中，相对而言似乎有更多病例起源于国外而非整个英国，但这一比例已逐渐下降至接近全国水平。随着英国淋球菌感染总数逐渐下降，产青霉素酶淋球菌感染的比例却持续上升。密切监测这一情况、在必要时审查治疗建议并对局部流行保持警惕非常重要。
