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卡路里计数:炎症的代价。

Counting Calories: The Cost of Inflammation.

机构信息

Department of Medicine (Rheumatology), Yale University School of Medicine, New Haven, CT 06520, USA.

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520, USA.

出版信息

Cell. 2019 Apr 4;177(2):223-224. doi: 10.1016/j.cell.2019.03.022.

Abstract

A relationship between thermoregulation, metabolism, and the host response to infections has long been appreciated. In this study, Ganeshan and colleagues discover that the immune system regulates body temperature as a strategy to regulate metabolic rate, which in turn promotes tolerance to inflammatory damage.

摘要

体温调节、新陈代谢和宿主对感染的反应之间的关系早已被人们所认识。在这项研究中,Ganeshan 及其同事发现,免疫系统调节体温是一种调节代谢率的策略,而代谢率的调节又反过来促进了对炎症损伤的耐受。

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