Brooks L D, Marks R W
Genetics. 1986 Oct;114(2):525-47. doi: 10.1093/genetics/114.2.525.
The amount and form of natural genetic variation for recombination were studied in six lines for which second chromosomes were extracted from a natural population of Drosophila melanogaster. Multiply marked second, X and third chromosomes were used to score recombination. Recombination in the second chromosomes varied in both amount and distribution. These second chromosomes caused variation in the amount and distribution of crossing over in the X chromosome and also caused variation in the amount, but not the distribution, of crossing over in the third chromosome. The total amount of crossing over on a chromosome varied by 12-14%. One small region varied twofold; other regions varied by 16-38%. Lines with less crossing over on one chromosome generally had less crossing over on other chromosomes, the opposite of the standard interchromosomal effect. These results show that modifiers of recombination can affect more than one chromosome, and that the variation exists for fine-scale response to selection on recombination.
在从黑腹果蝇自然种群中提取出第二染色体的六个品系中，研究了重组的自然遗传变异的数量和形式。使用多重标记的第二、X和第三染色体来记录重组情况。第二染色体中的重组在数量和分布上均有所不同。这些第二染色体导致X染色体上交换的数量和分布发生变化，也导致第三染色体上交换的数量发生变化，但分布不变。一条染色体上交换的总量变化了12 - 14%。一个小区域的变化为两倍；其他区域的变化为16 - 38%。在一条染色体上交换较少的品系，在其他染色体上通常也有较少的交换，这与标准的染色体间效应相反。这些结果表明，重组修饰因子可以影响不止一条染色体，并且存在对重组选择的精细尺度响应的变异。
