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单剂量氨曲南治疗单纯性淋病

Treatment of uncomplicated gonorrhoea with single dose aztreonam.

作者信息

Evans D T, Crooks A J, Jones C, Holman R A, Price S W

出版信息

Genitourin Med. 1986 Oct;62(5):318-20. doi: 10.1136/sti.62.5.318.

Abstract

Infection with Neisseria gonorrhoeae was cleared in 61 men and 26 women at all sites (except in the pharynx of one male bisexual patient with urethral and pharyngeal gonorrhoea) after treatment with aztreonam as a single 1 g intramuscular injection. Aztreonam was well tolerated with no adverse effects. This monobactam antibiotic was effective against both penicillin sensitive and resistant strains.

摘要

61名男性和26名女性在接受单剂量1克氨曲南肌肉注射治疗后,所有部位(一名患有尿道和咽部淋病的男性双性恋患者的咽部除外)的淋病奈瑟菌感染均得到清除。氨曲南耐受性良好,无不良反应。这种单环β-内酰胺类抗生素对青霉素敏感和耐药菌株均有效。

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引用本文的文献

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In-vivo properties of SQ 26,776.SQ 26,776的体内特性。
J Antimicrob Chemother. 1981 Dec;8 Suppl E:123-30. doi: 10.1093/jac/8.suppl_e.123.
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In-vitro activity of monobactam, SQ 26,776, against Gram-negative bacteria.
J Antimicrob Chemother. 1981 Dec;8 Suppl E:49-55. doi: 10.1093/jac/8.suppl_e.49.
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Immunology of the monobactam aztreonam.单环β-内酰胺类抗生素氨曲南的免疫学
Antimicrob Agents Chemother. 1984 Jan;25(1):93-7. doi: 10.1128/AAC.25.1.93.
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Effectiveness of aztreonam for the treatment of gonorrhea.氨曲南治疗淋病的有效性。
Antimicrob Agents Chemother. 1985 Feb;27(2):270-1. doi: 10.1128/AAC.27.2.270.

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