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希腊出现属于东欧亚分支的西尼罗河病毒2型毒株。

Emergence of West Nile virus lineage 2 belonging to the Eastern European subclade, Greece.

作者信息

Papa Anna, Papadopoulou Elpida, Chatzixanthouliou Charikleia, Glouftsios Petros, Pappa Styliani, Pervanidou Danai, Georgiou Loukas

机构信息

Department of Microbiology, National Reference Centre for Arboviruses and Hemorrhagic Fever viruses, Medical School, Aristotle University of Thessaloniki, 51124, Thessaloníki, Greece.

Internal Medicine Clinic, Didimoticho General Hospital, Didimoticho, Greece.

出版信息

Arch Virol. 2019 Jun;164(6):1673-1675. doi: 10.1007/s00705-019-04243-8. Epub 2019 Apr 5.

DOI:10.1007/s00705-019-04243-8
PMID:30953205
Abstract

West Nile virus (WNV) emerged in Greece in 2010 and since then human outbreaks occurred every year except 2015 and 2016. An early start and prolonged WNV transmission season was observed in 2018 with a record number of 316 reported cases and 47 fatalities. The Greek WNV strains detected during 2010-2018 clustered within the central European subclade of lineage 2. A novel WNV genetic variant was detected in August 2018 in one human case in the north-eastern region of Greece, at the land cross-border with Turkey and Bulgaria. The strain belongs to the Eastern European subclade of lineage 2 suggesting a new virus introduction in the country and the continuously changing epidemiology of the disease.

摘要

西尼罗河病毒(WNV)于2010年在希腊出现,自那时起,除了2015年和2016年外,每年都有人类疫情爆发。2018年观察到西尼罗河病毒传播季节开始早且持续时间长,报告病例数创纪录地达到316例,死亡47人。2010 - 2018年期间在希腊检测到的西尼罗河病毒株聚集在2型谱系的中欧亚分支内。2018年8月,在希腊东北部与土耳其和保加利亚接壤的陆地边境的一例人类病例中检测到一种新型西尼罗河病毒基因变体。该毒株属于2型谱系的东欧亚分支,表明该国出现了新的病毒引入,且该疾病的流行病学在不断变化。

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