2013 年 8 月，意大利人感染西尼罗河病毒 1 型和 2 型的全基因组测序和系统进化分析。
Whole genome sequencing and phylogenetic analysis of West Nile virus lineage 1 and lineage 2 from human cases of infection, Italy, August 2013.
机构信息
Department of Molecular Medicine, University of Padova, Padova, Italy.
出版信息
Euro Surveill. 2013 Sep 19;18(38):20591. doi: 10.2807/1560-7917.es2013.18.38.20591.
A human outbreak of West Nile virus (WNV) infection caused by WNV lineage 2 is ongoing in northern Italy. Analysis of six WNV genome sequences obtained from clinical specimens demonstrated similarities with strains circulating in central Europe and Greece and the presence of unique amino acid changes that identify a new viral strain. In addition, WNV lineage 1 Livenza, responsible for a large outbreak in north-eastern Italy in 2012, was fully sequenced from a blood donor during this 2013 outbreak.
意大利北部正在发生由西尼罗河病毒（WNV）谱系 2 引起的人类 WNV 感染疫情。对从临床标本中获得的 6 个 WNV 基因组序列的分析表明，它们与在中欧和希腊流行的毒株相似，并且存在独特的氨基酸变化，可鉴定出新的病毒株。此外，在这次 2013 年的疫情中，对来自一位献血者的样本进行了全面测序，发现导致 2012 年意大利东北部大规模疫情的 Livenza 谱系 1 也存在于其中。
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