Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Connecticut.
Hospitalist Program, University of California, Irvine, California.
Heart Rhythm. 2019 Aug;16(8):e59-e65. doi: 10.1016/j.hrthm.2019.04.007. Epub 2019 Apr 5.
The prevalence of both atrial fibrillation (AF) and stroke is increasing. Stroke is common in AF and can have devastating consequences, especially when AF is unrecognized and anticoagulation is not initiated.
The purpose of this study was to demonstrate the feasibility and yield, both in identifying previously undiagnosed AF and in educating patients and caregivers about AF, of systematic screening events in internal medicine practices using a mobile electrocardiogram device (Kardia/AliveCor iECG).
With support from the Heart Rhythm Society and the American College of Physicians, 5 internal medicine practices performed systematic screening and education of patients at higher risk of AF using the Kardia/AliveCor device and a variety of educational materials. Patients screened as "unclassified" or "possible AF" were referred for further evaluation. Patients and providers (physicians, nurses, and allied professionals) assessed the screening process.
A total of 772 patients were screened. The mean age was 65.2 ± 15.4 years, and 281 (28.2%) were 75 years or older. The majority, 521 (67.5%), were female, and 586 (75.7%) had a CHADS-VASc score of ≥2. Six hundred seventy patients (86.8%) were screened as "normal," 85 (11.0%) as "unclassified," and 17 (2.2%) as "possible AF." Participants demonstrated a significant knowledge deficit about stroke and AF before the screening events, and the majority felt that their awareness of these issues increased significantly as a result of their participation.
This collaborative Heart Rhythm Society/American College of Physicians systematic screening effort using the Kardia/AliveCor device was feasible. Although it resulted in a relatively modest yield of "unclassified" or "possible AF" screens, it had significant educational benefit to participants and caregivers. The diagnostic yield of future programs could be enriched by including more elderly patients and those with more risk factors for AF and stroke. A greater duration or frequency of monitoring would likely increase sensitivity but be more complicated and costlier to administer. Future events should include on-site confirmatory testing with a 12-lead electrocardiogram. Devices such as the Kardia/AliveCor monitor may enhance patient engagement in screening programs.
心房颤动(AF)和中风的患病率都在增加。中风在 AF 中很常见,可能会产生毁灭性的后果,尤其是当 AF 未被识别且未开始抗凝治疗时。
本研究旨在展示使用移动心电图设备(Kardia/AliveCor iECG)在内科实践中进行系统筛查的可行性和效果,包括识别先前未诊断的 AF 以及教育患者和护理人员。
在心律学会和美国医师学院的支持下,5 家内科诊所使用 Kardia/AliveCor 设备和各种教育材料对 AF 风险较高的患者进行系统筛查和教育。筛查为“未分类”或“可能的 AF”的患者被转介进行进一步评估。患者和提供者(医生、护士和相关专业人员)评估了筛查过程。
共有 772 名患者接受了筛查。平均年龄为 65.2±15.4 岁,281 名(28.2%)患者年龄在 75 岁或以上。大多数患者(521 名,67.5%)为女性,586 名(75.7%)患者的 CHADS-VASc 评分为≥2。670 名患者(86.8%)的筛查结果为“正常”,85 名(11.0%)为“未分类”,17 名(2.2%)为“可能的 AF”。在筛查前,参与者对中风和 AF 的知识存在明显的不足,并且大多数人认为,他们通过参与这项活动,对这些问题的认识有了显著的提高。
这项由心律学会和美国医师学院合作进行的使用 Kardia/AliveCor 设备的系统筛查工作是可行的。尽管它导致“未分类”或“可能的 AF”筛查的结果相对较低,但对参与者和护理人员具有重要的教育意义。未来的项目可以通过纳入更多的老年患者和具有更多 AF 和中风风险因素的患者,来丰富其诊断效果。更长的监测时间或更高的监测频率可能会提高灵敏度,但管理起来会更加复杂且费用更高。未来的活动应包括现场使用 12 导联心电图进行确认性测试。像 Kardia/AliveCor 监测器这样的设备可能会增强患者对筛查计划的参与度。