Lytton E J, Blake M S
J Exp Med. 1986 Nov 1;164(5):1749-59. doi: 10.1084/jem.164.5.1749.
We have isolated and purified the reduction-modifiable protein (protein III) from several strains of Neisseria gonorrhoeae. We have found them to be basic proteins (pI 8.6) and virtually identical. A similar but not identical protein was isolated from a meningococcal strain. Antibodies raised against this purified protein would absorb to whole bacteria, confirming that the protein is exposed on the surface of the organism.
我们已从数株淋病奈瑟菌中分离并纯化出还原可修饰蛋白(蛋白III)。我们发现它们是碱性蛋白(pI 8.6)且几乎完全相同。从一株脑膜炎球菌中分离出了一种类似但不完全相同的蛋白。针对这种纯化蛋白产生的抗体能与完整细菌结合,证实该蛋白暴露于该生物体表面。