Al-Dahery S, McGee A, Rainford L, Khashoggi K, Misha N
Radiography and Diagnostic Imaging, School of Medicine, University College Dublin, Dublin, Ireland.
Radiography and Diagnostic Imaging, School of Medicine, University College Dublin, Dublin, Ireland.
Radiography (Lond). 2019 May;25(2):e45-e51. doi: 10.1016/j.radi.2018.10.005. Epub 2018 Nov 22.
This multi-site study evaluated two breath-hold sequences commonly utilised for liver MRI; non-enhanced T1W-3D-FS-GRE-TRA and T2W-2D-FSE-TRA sequences, using physical measurements of SNR and CNR, and observer perceptions' (Visual Grading Analysis: VGA).
Liver MR image datasets (n = 168) from nine hospitals in the Kingdom of Saudi Arabia (KSA) and 11 hospitals in the Republic of Ireland were evaluated. Images were categorised into two groups per sequence, defined by slice thickness (T2W-2D-FSE, ≤5 mm vs ≥ 6 mm and T1W-3D-GRE-FS, ≤3 mm vs 4 mm). Images were evaluated using visual grading analysis VGA and physical measurements: SNR/CNR. Account was taken of varying patient sizes based on AP/transverse diameter measurements.
Physical image quality measurements (SNR/CNR) returned no significant findings across Irish and KSA hospitals, for both sequences, despite variations in acquisition parameters. Statistically significant differences were found for some scoring criteria based on the observers' perceptions including spleen parenchyma, and spatial resolution for the non-enhanced T1W-3D-FS-GRE-TRA images, with a preference for images acquired using thin slices (≤3 mm). In addition, statistically significant difference was found for the scoring criteria motion artefact for the axial T2W-2D-FSE-TRA images, with a preference for images acquired using thick slices (≥5 mm). Negligible correlation was noted between SNR/CNR and measured abdominal AP/transverse diameters.
Whilst variations in sequences rendered no statistical differences in SNR/CNR findings, significant differences in observer image criteria scores was noted. The importance of both physical measurements and observers' perceptions evaluation methods for quality assessment of MR images was demonstrated and optimisation of liver sequence parameters is warranted.
本多中心研究评估了肝脏MRI常用的两种屏气序列;未增强的T1W-3D-FS-GRE-TRA序列和T2W-2D-FSE-TRA序列,采用信噪比(SNR)和对比噪声比(CNR)的物理测量以及观察者的主观感受(视觉分级分析:VGA)。
对来自沙特阿拉伯王国(KSA)9家医院和爱尔兰共和国11家医院的肝脏MR图像数据集(n = 168)进行评估。图像按每个序列分为两组,根据层厚定义(T2W-2D-FSE,≤5mm与≥6mm;T1W-3D-GRE-FS,≤3mm与4mm)。使用视觉分级分析VGA和物理测量(SNR/CNR)对图像进行评估。根据前后径/横径测量结果考虑了不同患者体型的差异。
尽管采集参数存在差异,但在爱尔兰和KSA的医院中,两种序列的物理图像质量测量(SNR/CNR)均未得出显著结果。基于观察者主观感受的一些评分标准存在统计学显著差异,包括脾脏实质以及未增强的T1W-3D-FS-GRE-TRA图像的空间分辨率,观察者更倾向于薄层(≤3mm)采集的图像。此外,轴向T2W-2D-FSE-TRA图像的运动伪影评分标准存在统计学显著差异,观察者更倾向于厚层(≥5mm)采集的图像。SNR/CNR与测量的腹部前后径/横径之间的相关性可忽略不计。
虽然序列变化在SNR/CNR结果上未产生统计学差异,但观察者图像标准评分存在显著差异。证明了物理测量和观察者主观感受评估方法对MR图像质量评估的重要性,肝脏序列参数的优化是必要的。