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长春花碱、顺铂、环磷酰胺、博来霉素、多柔比星和依托泊苷(VPCBAE)用于三名卵巢小细胞癌患者的治疗。

Vinblastine, cisplatin, cyclophosphamide, bleomycin, doxorubicin, and etoposide (VPCBAE) in the management of three patients with small-cell carcinoma of the ovary.

作者信息

Wallbillich John J, Nick Alpa M, Ramirez Pedro T, Watkins Jack L, Euscher Elizabeth D, Schmeler Kathleen M

机构信息

Department of Obstetrics, Gynecology and Reproductive Sciences, The University of Texas Health Science Center at Houston, Houston, TX, USA.

Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

出版信息

Gynecol Oncol Case Rep. 2012 Feb 13;2(2):58-60. doi: 10.1016/j.gynor.2012.02.001. eCollection 2012.

DOI:10.1016/j.gynor.2012.02.001
PMID:24371617
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3860786/
Abstract

► Ovarian small-cell carcinoma of the hypercalcemic type is a rare neoplasm with no standard treatment. ► The chemotherapy regimen including vinblastine, cisplatin, cyclophosphamide, bleomycin, doxorubicin and etoposide (VPCBAE) has limited toxicities and was effective in the 3 patients described in this case report.

摘要

► 高钙血症型卵巢小细胞癌是一种罕见的肿瘤,尚无标准治疗方法。► 包括长春碱、顺铂、环磷酰胺、博来霉素、阿霉素和依托泊苷(VPCBAE)的化疗方案毒性有限,在本病例报告中描述的3例患者中有效。

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Vinblastine, cisplatin, cyclophosphamide, bleomycin, doxorubicin, and etoposide (VPCBAE) in the management of three patients with small-cell carcinoma of the ovary.长春花碱、顺铂、环磷酰胺、博来霉素、多柔比星和依托泊苷(VPCBAE)用于三名卵巢小细胞癌患者的治疗。
Gynecol Oncol Case Rep. 2012 Feb 13;2(2):58-60. doi: 10.1016/j.gynor.2012.02.001. eCollection 2012.
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Cancer. 1989 Sep 15;64(6):1183-7. doi: 10.1002/1097-0142(19890915)64:6<1183::aid-cncr2820640603>3.0.co;2-n.
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本文引用的文献

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Survival and reproductive outcomes in women treated for malignant ovarian germ cell tumors.女性恶性卵巢生殖细胞肿瘤治疗的生存和生殖结局。
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Advanced-stage small cell carcinoma of the ovary in pregnancy: long-term survival after surgical debulking and multiagent chemotherapy.妊娠期晚期卵巢小细胞癌:手术减瘤及多药化疗后的长期生存
Gynecol Oncol. 1997 Sep;66(3):531-4. doi: 10.1006/gyno.1997.4801.
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Small cell carcinoma of the ovary, hypercalcemic type. A clinicopathological analysis of 150 cases.卵巢小细胞癌,高钙血症型。150例临床病理分析。
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Vinblastine, cisplatin, cyclophosphamide, bleomycin, doxorubicin, and etoposide in the treatment of small cell carcinoma of the ovary.长春花碱、顺铂、环磷酰胺、博来霉素、多柔比星和依托泊苷用于治疗卵巢小细胞癌。
Cancer. 1989 Sep 15;64(6):1183-7. doi: 10.1002/1097-0142(19890915)64:6<1183::aid-cncr2820640603>3.0.co;2-n.