Popov Vladimir V, Muller-Kamskii Gary, Katz-Demyanetz Alexander, Kovalevsky Aleksey, Usov Stas, Trofimcow Dmitrii, Dzhenzhera Georgy, Koptyug Andrey
1Israel Institute of Metals, Technion R&D Foundation, 32000 Technion City, Haifa, Israel.
Veterinary Clinic Ortho-Vet, Saint-Petersburg, Russia.
Biomed Eng Lett. 2019 Jan 4;9(1):97-108. doi: 10.1007/s13534-018-00092-7. eCollection 2019 Feb.
The paper outlines the achievements and challenges in the additive manufacturing (AM) application to veterinary practice. The state-of-the-art in AM application to the veterinary surgery is presented, with the focus of AM for patient-specific implants manufacturing. It also provides critical discussion on some of the potential issues design and technology should overcome for wider and more effective implementation of additively manufactured parts in veterinary practices. Most of the discussions in present paper are related to the metallic implants, manufactured in this case using so-called powder bed additive manufacturing (PB-AM) in titanium alloy Ti-6AL-4V, and to the corresponding process of their design, manufacturing and implementation in veterinary surgery. Procedures of the implant design and individualization for veterinary surgery are illustrated basing on the four performed surgery cases with dog patients. Results of the replacement surgery in dogs indicate that individualized additively manufactured metallic implants significantly increase chances for successful recovery process, and AM techniques present a viable alternative to amputation in a large number of veterinary cases. The same time overcoming challenges of implant individualization in veterinary practice significantly contributes to the knowledge directly relevant to the modern medical practice. An experience from veterinary cases where organ-preserving surgery with 3D-printed patient-specific implants is performed provides a unique opportunity for future development of better human implants.
本文概述了增材制造（AM）在兽医实践中的应用成果与挑战。介绍了AM在兽医外科手术中的应用现状，重点是用于制造个性化植入物。本文还对设计和技术在兽医实践中更广泛、更有效地应用增材制造部件时应克服的一些潜在问题进行了批判性讨论。本文的大部分讨论都与金属植入物有关，在这种情况下，使用钛合金Ti-6AL-4V通过所谓的粉末床增材制造（PB-AM）来制造金属植入物，并涉及它们在兽医外科手术中的设计、制造和应用过程。基于对四只犬科病犬进行的手术案例，阐述了兽医外科手术中植入物设计和个性化的程序。犬类置换手术的结果表明，个性化增材制造的金属植入物显著增加了成功康复的几率，并且AM技术在大量兽医病例中是截肢的可行替代方案。同时，克服兽医实践中植入物个性化的挑战对与现代医学实践直接相关的知识有显著贡献。在兽医病例中使用3D打印的个性化植入物进行器官保留手术的经验为未来开发更好的人类植入物提供了独特的机会。
