薰衣草油芳香疗法对学业压力的评估：一项随机安慰剂对照临床试验。

Evaluation of aromatherapy with lavender oil on academic stress: A randomized placebo controlled clinical trial.

作者信息

Ahmad Rizwan, Naqvi Atta Abbas, Al-Bukhaytan Hamdan Moayed, Al-Nasser Ahmed Habib, Baqer Al-Ebrahim Ali Hassan

机构信息

Natural Products and Alternative Medicines, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia.

Department of Pharmacy Practice, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia.

出版信息

Contemp Clin Trials Commun. 2019 Mar 15;14:100346. doi: 10.1016/j.conctc.2019.100346. eCollection 2019 Jun.

INTRODUCTION

Academic stress is prevalent among pharmacy students. Several factors such as hectic schedules, courses and exam load as well as lack of recreational time during semester have been reported as determinants of academic stress. Studies revealed; the use of aroma oils especially with relaxant properties may help ease stress.

METHODS

This study aimed to investigate the effect of lavender oil on academic stress during exams in pharmacy students. A randomized-single-blind placebo-controlled trial providing aromatherapy with lavender oil as an intervention was conducted in male pharmacy students. The outcomes assessed included stress, stool pattern, headache and vital signs that comprised of systolic, diastolic blood pressure (SBP and DBP) and heart rate (HR). The study was approved from concerned authority and registered in ClinicalTrials.gov (NCT#03460626).

RESULTS

The placebo and experimental group showed a significant (p < 0.01) difference in stress score (F = 244.865, p < 0.0001), headache VAS score (F = 8.187, p < 0.0001), SBP (F = 11.141, p < 0.0001), DBP (F = 3.873, p < 0.001) and HR (F = 8.537, p < 0.0001); at during-exam time-point as compared to control group. No significance was achieved; among three treatment groups in stool pattern (F = 2.143, p > 0.05) and, at post-exam time-point (p > 0.05).

CONCLUSION

Aromatherapy with lavender oil did not have any effect on academic stress.

TRIAL REGISTRATION

The study was registered prospectively on ClinicalTrials.gov (NCT#03460626) on 19th February 2018.

引言

学业压力在药学专业学生中普遍存在。据报道，诸如日程安排紧张、课程和考试负担以及学期中缺乏娱乐时间等多种因素是学业压力的决定因素。研究表明，使用具有放松特性的香薰油可能有助于缓解压力。

方法

本研究旨在调查薰衣草油对药学专业学生考试期间学业压力的影响。在男性药学专业学生中进行了一项随机单盲安慰剂对照试验，以薰衣草油进行芳香疗法作为干预措施。评估的结果包括压力、排便模式、头痛以及由收缩压、舒张压（SBP和DBP）和心率（HR）组成的生命体征。该研究获得了相关部门的批准，并在ClinicalTrials.gov（NCT#03460626）上注册。

结果

与对照组相比，安慰剂组和实验组在考试期间的压力评分（F = 244.865，p < 0.0001）、头痛视觉模拟评分（F = 8.187，p < 0.0001）、收缩压（F = 11.141，p < 0.0001）、舒张压（F = 3.873，p < 0.001）和心率（F = 8.537，p < 0.0001）方面存在显著差异（p < 0.01）。在排便模式方面，三个治疗组之间没有显著差异（F = 2.143，p > 0.05），在考试后时间点也没有显著差异（p > 0.05）。