海洋海绵来源真菌的两种新化合物。
Two new compounds from the marine sponge derived fungus .
机构信息
School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
Laboratory of Marine Drugs and Biological Products, National Laboratory for Marine Science and Technology, Qingdao, China.
出版信息
Nat Prod Res. 2020 Oct;34(20):2926-2930. doi: 10.1080/14786419.2019.1598994. Epub 2019 Apr 8.
Abstract
Two new compounds ( and ) were isolated from the marine sponge derived fungus by using various column chromatography techniques. Their structures were elucidated by extensive analysis of spectroscopic data and quantum chemical calculation. Compound exhibited moderate activity against PTP1B with 2.95 ± 0.97% at the concentration of 30 μmol·L.
摘要
两种新化合物（和）从海洋海绵源真菌通过使用各种柱层析技术分离得到。通过广泛的光谱数据分析和量子化学计算，确定了它们的结构。化合物对 PTP1B 表现出中等活性，在 30 μmol·L 的浓度下为 2.95±0.97%。
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