Gonzalo J, Perul M, Corral M, Caballero M, Conti C, García D, Vassena R, Rodríguez A
a Clínica EUGIN , Barcelona , Spain.
Eur J Contracept Reprod Health Care. 2019 Jun;24(3):227-232. doi: 10.1080/13625187.2019.1588960. Epub 2019 Apr 8.
The aim of this study is to evaluate the health of oocyte donors and explain how they regard their experience in the long-term. This is a cross-sectional study in a single fertility centre that consists of a telephone interview guided by a semi-structured questionnaire covering several aspects of reproductive health and personal experience. At the time of interview, 84 out of 121 women (69%) had children while 64 (53%) were already mothers at the time of their donation. Of the 38 women achieving a pregnancy after donation, five reported six pregnancy complications. Two out of 121 (2%) women reported being in menopause (aged 41 and 45). Twenty-three women (19%) reported gynaecological issues and eight (7%) reported fertility problems, although only four consulted a specialist. Most of women highlighted positive feelings about their donation (113, 93%) and 155 (97%) would recommend donating. Less than half (53, 44%) mentioned some negative aspects, mainly related to physical discomfort: injections (20,17%), pain (17, 14%), and side effects of ovarian stimulation (10, 8%). The impact of donation on women's life was mostly favourable, with the majority of participants reporting positive aspects and recommending donation, although some negative feelings as physical discomfort also arose. Therefore, more comfortable stimulation protocols could be developed.
本研究的目的是评估卵母细胞捐赠者的健康状况,并解释她们对自身长期经历的看法。这是一项在单一生育中心进行的横断面研究,包括一次电话访谈,访谈由一份涵盖生殖健康和个人经历多个方面的半结构化问卷引导。在访谈时,121名女性中有84名(69%)育有子女,64名(53%)在捐赠时已成为母亲。在38名捐赠后怀孕的女性中,有5名报告了6次妊娠并发症。121名女性中有2名(2%)报告已绝经(年龄分别为41岁和45岁)。23名女性(19%)报告有妇科问题,8名(7%)报告有生育问题,不过只有4人咨询过专科医生。大多数女性强调了她们对捐赠的积极感受(113名,93%),155名(97%)会推荐捐赠。不到一半(53名,44%)提到了一些负面方面,主要与身体不适有关:注射(20名,17%)、疼痛(17名,14%)和卵巢刺激的副作用(10名,8%)。捐赠对女性生活的影响大多是积极的,大多数参与者报告了积极方面并推荐捐赠,尽管也出现了一些如身体不适等负面感受。因此,可以制定更舒适的刺激方案。