LAPAROSCOPIC NISSEN ROSETTI FUNDOPLICATION IN TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE: EVALUATION OF LONG TERM CLINICAL OUTCOMES AND QUALITY OF LIFE.

The aim of this study is to evaluate outcomes of Nissen-Rossetti fundoplication in-terms of objective measures and quality of life evaluation instruments. For the period in observation, the chronic GERD patients, who had undergone LNRF surgery, were evaluated. The long-term outcome was assessed by subjectively comparing the preoperative and postoperative symptoms and Gastroesophageal reflux-Health related quality of life index. As an objective assessment of the pathological reflux, patients underwent 24-hour pH monitoring in the preoperative and postoperative period. Thirty-two patients, who met the criteria and volunteered to participate, were included in the study. The median postoperative follow-up period for the patients was 28±7.92 (16-52) months. A significant increase was observed in the quality of life scores in the postoperative period when compared to the preoperative period (p=0.001) and the DeMeester scores have decreased significantly (p=0.001). The postoperative dysphagia was observed even in the long term in most of the patients, without having a significant effect on the quality of life. In the treatment of gastroesophageal reflux disease, laparoscopic Nissen Rossetti fundoplication is an effective and successful method in achieving the desired outcome such as preventing pathological reflux, relieving the symptoms and improving the quality of life in the long term.