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电子烟使用者呼出气体中的一氧化碳及尿可替宁水平

Carbon Monoxide in the Expired Air and Urinary Cotinine Levels of e-Cigarette Users.

作者信息

Aslan Dilek, Gürbay Aylin, Hayran Mutlu, Şengelen Meltem, Paslı Duygu, Hüseyin Beril

机构信息

Department of Public Health, Hacettepe University School of Medicine, Ankara, Turkey.

Department of Pharmaceutical Toxicology, Hacettepe University Faculty of Pharmacy, Ankara, Turkey.

出版信息

Turk Thorac J. 2019 Apr 1;20(2):125-129. doi: 10.5152/TurkThoracJ.2018.18110. Print 2019 Apr.

DOI:10.5152/TurkThoracJ.2018.18110
PMID:30958985
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6453636/
Abstract

OBJECTIVES

The aim of this descriptive study was to determine the sociodemographic characteristics of electronic (e)-cigarette users for clarifying the causes of e-cigarette smoking and to identify the carbon monoxide (CO) and urinary cotinine levels of the volunteers.

MATERIALS AND METHODS

Twenty volunteers who smoked e-cigarettes completed a questionnaire, and their exhaled CO and urinary cotinine levels were measured. An enzyme-linked immunosorbent assay kit was used for cotinine analysis.

RESULTS

Overall, 85% of the participants were males, 60% were married, and 75% were college/university graduates. The median age of participants was 38.5 years. The participants' main reasons for starting to smoke were peer influence and curiosity. The participants' main reasons for smoking e-cigarettes were to quit and reduce smoking the conventional cigarettes and cost effectiveness. Only three people knew that smoking was harmful to health. The participants' CO levels were measured as a median of 3, lowest of 1, and highest of 22. Cotinine levels were "positive" in all samples. A moderate and statistically significant correlation was found between the amount of fluids used by the participants in 1 day (mL) and cotinine levels in urine specimens (Pearson correlation test, r=0.511, p=0.025).

CONCLUSION

The study is an important proof of the country's scientific work on e-cigarettes. Preventive strategies should be very strictly implemented for any tobacco products, including e-cigarettes, as they harm individuals and the community.

摘要

目的

本描述性研究旨在确定电子烟使用者的社会人口学特征,以阐明吸电子烟的原因,并确定志愿者的一氧化碳(CO)和尿可替宁水平。

材料与方法

20名吸电子烟的志愿者完成了一份问卷,并测量了他们呼出的CO和尿可替宁水平。使用酶联免疫吸附测定试剂盒进行可替宁分析。

结果

总体而言,85%的参与者为男性,60%已婚,75%为大学毕业生。参与者的中位年龄为38.5岁。参与者开始吸烟的主要原因是同伴影响和好奇心。参与者吸电子烟的主要原因是戒烟、减少吸传统香烟以及成本效益。只有三人知道吸烟有害健康。参与者的CO水平测量结果中位数为3,最低为1,最高为22。所有样本的可替宁水平均为“阳性”。在参与者一天使用的液体量(毫升)与尿液样本中的可替宁水平之间发现了中度且具有统计学意义的相关性(Pearson相关检验,r = 0.511,p = 0.025)。

结论

该研究是该国关于电子烟科学工作的一项重要证据。对于包括电子烟在内的任何烟草制品,都应非常严格地实施预防策略,因为它们会危害个人和社区。

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