天花疫苗接种后出现急性髓系白血病的现役军人的先发 Tecovirimat 治疗。
Preemptive Tecovirimat Use in an Active Duty Service Member Who Presented With Acute Myeloid Leukemia After Smallpox Vaccination.
机构信息
Infectious Disease Service, Joint Base San Antonio-Fort Sam Houston, Texas.
Department of Medicine, San Antonio Military Medical Center, Joint Base San Antonio-Fort Sam Houston, Texas.
出版信息
Clin Infect Dis. 2019 Nov 27;69(12):2205-2207. doi: 10.1093/cid/ciz286.
PMID:30959520
Abstract
Smallpox vaccine is contraindicated in immunosuppression due to increased risk for adverse reactions (eg, progressive vaccinia). We describe the first-ever use of tecovirimat as a preemptive vaccinia virus treatment strategy during induction chemotherapy in an active duty service member who presented with acute leukemia and inadvertent autoinoculation after smallpox vaccination.
摘要
天花疫苗在免疫抑制情况下禁忌使用，因为不良反应风险增加（例如，进行性牛痘）。我们描述了泰诺福韦酯在现役军人接受诱导化疗期间，对因接种天花疫苗而导致急性白血病和意外自身接种的患者进行预防性牛痘病毒治疗的首例应用。
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