Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, B15 2TT, Birmingham, UK.
Arthritis Res Ther. 2019 Apr 8;21(1):90. doi: 10.1186/s13075-019-1871-5.
Rheumatoid arthritis is an immune-mediated inflammatory disease of the synovium. Yet we still lack robust tissue-specific (synovial) biomarkers that are able to guide clinical decisions and stratify patients according to their disease subgroup and predicted response to treatment. The EULAR Synovitis Study Group and the OMERACT synovial tissue biopsy (STB) Special Interests Group have undertaken a consensus exercise to identify factors that are important for the standardisation of STB handling and analytical procedures in two situations-clinical practice and translational research.
类风湿关节炎是一种滑膜介导的免疫炎症性疾病。然而，我们仍然缺乏强大的组织特异性（滑膜）生物标志物，这些标志物能够根据疾病亚组和对治疗的预测反应来指导临床决策和对患者进行分层。EULAR 滑膜炎研究组和 OMERACT 滑膜组织活检（STB）特别兴趣小组进行了一项共识性工作，以确定在临床实践和转化研究两种情况下，对 STB 处理和分析程序进行标准化的重要因素。
