Reagan Krystle L, Sykes Jane E
Veterinary Medical Teaching Hospital, University of California, 1 Shields Ave Davis, CA 95616, USA.
Department of Medicine and Epidemiology, University of California, 1 Shields Ave Davis, CA 95616, USA.
Vet Clin North Am Small Anim Pract. 2019 Jul;49(4):719-731. doi: 10.1016/j.cvsm.2019.02.008. Epub 2019 Apr 6.
Several diagnostic tests are available to aid veterinarians in diagnosis of leptospirosis. Understanding the course of infection is imperative to determining which diagnostic test to order and sample to submit. Diagnostic tests for dogs suspected of having leptospirosis include antibody-based tests and polymerase chain reaction (PCR). Paired acute and convalescent microscopic agglutination test (MAT) are diagnostic for leptospirosis. PCR performed on blood and/or urine can be a valuable tool to aid in diagnosis of leptospirosis. Commercially available rapid point-of-care diagnostics have been validated in dogs and have value early in the course of illness before MAT and PCR results are available.
有几种诊断测试可帮助兽医诊断钩端螺旋体病。了解感染过程对于确定应进行哪种诊断测试以及提交何种样本至关重要。对疑似患有钩端螺旋体病的犬进行的诊断测试包括基于抗体的测试和聚合酶链反应（PCR）。成对的急性和恢复期显微镜凝集试验（MAT）可诊断钩端螺旋体病。对血液和/或尿液进行PCR检测可能是辅助诊断钩端螺旋体病的一项有价值的工具。市售的即时快速诊断方法已在犬身上得到验证，并且在获得MAT和PCR结果之前的疾病早期阶段具有重要价值。
