Ete Geley, Chaturvedi Gaurav, Barreto Elvino, Paul M Kingsly
Department of Plastic & Reconstructive Surgery, Christian Medical College, Vellore, Tamilnadu, India.
Department of Plastic & Reconstructive Surgery, Christian Medical College, Vellore, Tamilnadu, India.
Chin J Traumatol. 2019 Apr;22(2):113-116. doi: 10.1016/j.cjtee.2019.01.006. Epub 2019 Mar 2.
Acute burn resuscitation in initial 24 h remains a challenge to plastic surgeons. Though various formulae for fluid infusion are available but consensus is still lacking, resulting in under resuscitation or over resuscitation. Parkland formula is widely used but recently its adequacy is questioned in studies. This study was conducted to see how closely the actual volume of fluid given in our center matches with that of calculated volume by Parkland formula.
All patients admitted with more than 20% flame burn injury and within 8 h of incident were included in this study. Crystalloid solution for infusion was calculated as per Parkland formula; however, it was titrated according to the urine output. Data on fluid infusion were collected from patient's inpatient records and analyzed.
The study included a total of 90 patients, about 86.7% (n = 78) of the patients received fluid less than the calculated Parkland formula. Rate of fluid administered over 24 h in our study was 3.149 mL/kg/h. Mean hourly urine output was found to be 0.993 mL/kg/h. The mean difference between fluid administered and fluid calculated by Parkland formula was 3431.825 mL which was significant (p < 0.001).
The study showed a significant difference in the fluid infused based on urine output and the fluid calculated by Parkland formula. This probably is because fluid infused based on end point of resuscitation was more physiological than fluid calculated based on formulae.
对整形外科医生来说,烧伤后最初24小时的急性复苏仍是一项挑战。尽管有各种液体输注公式,但仍缺乏共识,导致复苏不足或过度复苏。帕克伦公式被广泛使用,但最近其适用性在研究中受到质疑。本研究旨在观察我们中心实际给予的液体量与帕克伦公式计算量的匹配程度。
本研究纳入了所有火焰烧伤面积超过20%且伤后8小时内入院的患者。根据帕克伦公式计算输注的晶体液量;然而,根据尿量进行滴定。从患者住院记录中收集液体输注数据并进行分析。
该研究共纳入90例患者,约86.7%(n = 78)的患者接受的液体量少于帕克伦公式计算量。我们研究中24小时内的液体输注速率为3.149 mL/kg/h。平均每小时尿量为0.993 mL/kg/h。实际给予的液体量与帕克伦公式计算的液体量之间的平均差值为3431.825 mL,具有显著性(p < 0.001)。
该研究表明,基于尿量输注的液体量与帕克伦公式计算的液体量存在显著差异。这可能是因为基于复苏终点输注的液体比基于公式计算的液体更符合生理情况。