A.C. Camargo Cancer Center, São Paulo, SP, Brazil.
A.C. Camargo Cancer Center, São Paulo, SP, Brazil.
Braz J Otorhinolaryngol. 2020 Sep-Oct;86(5):552-557. doi: 10.1016/j.bjorl.2019.02.004. Epub 2019 Mar 18.
Trismus has been considered a late complication of cancer treatment. It can occur prior to treatment, mainly caused by tumor invasion or muscle spasms induced by the presence of the tumor.
In this study, we evaluated the incidence of trismus and its effect on oral health in patients with malignant neoplasms of the oral cavity before performing the cancer treatment.
This review was carried out via interviews, visual clinical inspection and objective measurement of maximal mouth opening in 35 consecutive patients. Trismus was defined as a maximal mouth opening <35mm.
Trismus was observed in 15 patients, with a total incidence of 42%. A high rate of tooth loss was recorded, and trismus association with tooth loss was statistically verified using the Chi-square and Fisher's exact tests, the t-student test and Mann-Whitney non-parametric test. All tests were performed at p<0.05.
Edentulous patients are eight times more likely to have trismus compared to patients that are partially and fully dentate. Trismus was demonstrated to be correlated with tooth loss; however other oral health conditions were not shown to be a modifying factor.
牙关紧闭症被认为是癌症治疗的晚期并发症。它可能发生在治疗之前，主要是由肿瘤侵袭或肿瘤引起的肌肉痉挛引起的。
在进行癌症治疗之前，我们评估了口腔恶性肿瘤患者在接受癌症治疗前发生牙关紧闭症及其对口腔健康的影响。
本研究通过对 35 例连续患者进行访谈、视觉临床检查和最大张口度的客观测量来进行。牙关紧闭症定义为最大张口度<35mm。
15 例患者出现牙关紧闭症，总发生率为 42%。记录到较高的牙齿缺失率，并且使用卡方和 Fisher 确切检验、t 检验和曼-惠特尼非参数检验对牙关紧闭症与牙齿缺失的关系进行了统计学验证。所有检验均在 p<0.05 时进行。
与部分和完全有牙的患者相比，无牙患者发生牙关紧闭症的可能性高 8 倍。已经证明牙关紧闭症与牙齿缺失相关，但其他口腔健康状况不是一个修饰因素。
