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本文引用的文献

1
HPV-associated p16-expression and response to hypoxic modification of radiotherapy in head and neck cancer.HPV 相关的 p16 表达与头颈癌放射治疗缺氧修饰的反应。
Radiother Oncol. 2010 Jan;94(1):30-5. doi: 10.1016/j.radonc.2009.10.008. Epub 2009 Nov 10.
2
Expression of p16 in oral cancer and premalignant lesions.p16在口腔癌及癌前病变中的表达。
J Oral Pathol Med. 2009 Jan;38(1):104-8. doi: 10.1111/j.1600-0714.2008.00710.x.
3
Nomenclature and classification of potentially malignant disorders of the oral mucosa.口腔黏膜潜在恶性疾病的命名与分类
J Oral Pathol Med. 2007 Nov;36(10):575-80. doi: 10.1111/j.1600-0714.2007.00582.x.
4
Expression of p16(INK4A), p53, and Rb proteins are independent from the presence of human papillomavirus genes in oral squamous cell carcinoma.p16（INK4A）、p53和Rb蛋白的表达与口腔鳞状细胞癌中人类乳头瘤病毒基因的存在无关。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Sep;102(3):344-52. doi: 10.1016/j.tripleo.2005.10.069. Epub 2006 Mar 20.
5
Immunohistochemical detection of p16INK4a in dysplastic lesions of the oral cavity.口腔发育异常病变中p16INK4a的免疫组织化学检测
Mod Pathol. 2006 Oct;19(10):1310-6. doi: 10.1038/modpathol.3800649. Epub 2006 Jun 23.
6
Clinical significance of altered expression of retinoid receptors in oral precancerous and cancerous lesions: relationship with cell cycle regulators.类视黄醇受体表达改变在口腔癌前病变和癌性病变中的临床意义：与细胞周期调节因子的关系
Int J Cancer. 2006 Mar 1;118(5):1077-89. doi: 10.1002/ijc.21483.
7
Immunohistochemical assessment of Viadent-associated leukoplakia.
Oral Oncol. 2005 Feb;41(2):200-7. doi: 10.1016/j.oraloncology.2004.08.008.
8
Electron microscopy evidence that cytoplasmic localization of the p16(INK4A) "nuclear" cyclin-dependent kinase inhibitor (CKI) in tumor cells is specific and not an artifact. A study in non-small cell lung carcinomas.电子显微镜证据表明，肿瘤细胞中p16(INK4A)“核”细胞周期蛋白依赖性激酶抑制剂（CKI）的细胞质定位具有特异性，并非人为现象。一项针对非小细胞肺癌的研究。
Biotech Histochem. 2004 Feb;79(1):5-10. doi: 10.1080/10520290310001659466.
9
A subset of head and neck squamous cell carcinomas exhibits integration of HPV 16/18 DNA and overexpression of p16INK4A and p53 in the absence of mutations in p53 exons 5-8.一部分头颈部鳞状细胞癌在p53外显子5 - 8无突变的情况下，表现出HPV 16/18 DNA整合以及p16INK4A和p53的过表达。
Int J Cancer. 2003 Nov 10;107(3):394-400. doi: 10.1002/ijc.11389.
10
p16(INK4A) immunohistochemical overexpression in premalignant and malignant oral lesions infected with human papillomavirus.人乳头瘤病毒感染的口腔癌前病变和恶性病变中p16（INK4A）免疫组化过表达
J Histochem Cytochem. 2003 Oct;51(10):1291-7. doi: 10.1177/002215540305101006.

"Expression of p16 in oral leukoplakia and oral squamous cell carcinoma and correlation of its expression with individual atypical features".

作者信息

Agarwal Anshita, Kamboj Mala, Shreedhar Balasundari

机构信息

Career Post Graduate Institute of Dental Sciences, Lucknow, India.

Deptt. of Oral Pathology & Microbiology, Post Graduate Institute of Dental Sciences, Pt. BD Sharma University of Medical Sciences, Rohtak, Haryana, India.

出版信息

J Oral Biol Craniofac Res. 2019 Apr-Jun;9(2):156-160. doi: 10.1016/j.jobcr.2019.03.002. Epub 2019 Mar 11.

DOI:10.1016/j.jobcr.2019.03.002
PMID:30963022
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6434494/
Abstract
摘要