Brooks Peter J, Samuel Linsen T, Levin Jay M, Sultan Assem A, Khlopas Anton, Brigati David, Ng Mitchell, Greenwald A Seth, Mont Michael A
Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH, USA.
Department of Orthopaedic Surgery, Lenox Hill Hospital, New York, NY, USA.
Ann Transl Med. 2019 Feb;7(4):77. doi: 10.21037/atm.2019.01.39.
The aims of this study were to investigate the following questions: (I) what are the mortality rates in patients age 55 years and younger who underwent a hip resurfacing arthroplasty (HRA) versus a standard total hip arthroplasty (THA)? (II) is the type of operation independently associated with mortality?
The database of a single high-volume surgeon was reviewed for patient's age 55 years and younger who underwent a hip arthroplasty between 2002 and 2010. This yielded 505 HRA patients and 124 THA patients. Chi-square analysis was performed to identify a 5-year mortality rate difference between the two cohorts. Multivariable Cox-Regression analyses were used to determine whether the type of operation was independently associated with mortality.
There were 8 mortalities (1.6%) in the HRA cohort and 11 (8.9%) in the THA cohort, a statistically significant difference (P<0.001) on univariate analysis. Low mortality rates produced underpowered multivariate models.
We have demonstrated that patients age 55 and younger who undergo HRA have a significantly lower mortality rate than those undergoing THA. This is consistent with multiple previously published large database studies.
本研究的目的是调查以下问题:(I)55岁及以下接受髋关节表面置换术(HRA)与标准全髋关节置换术(THA)的患者的死亡率是多少?(II)手术类型是否与死亡率独立相关?
回顾了一位高手术量外科医生的数据库,纳入2002年至2010年间接受髋关节置换术的55岁及以下患者。这产生了505例HRA患者和124例THA患者。进行卡方分析以确定两组之间的5年死亡率差异。多变量Cox回归分析用于确定手术类型是否与死亡率独立相关。
HRA队列中有8例死亡(1.6%),THA队列中有11例(8.9%),单因素分析有统计学显著差异(P<0.001)。低死亡率导致多变量模型效能不足。
我们已经证明,55岁及以下接受HRA的患者的死亡率明显低于接受THA的患者。这与之前发表的多个大型数据库研究一致。