Seppänen Matti, Karvonen Mikko, Virolainen Petri, Remes Ville, Pulkkinen Pekka, Eskelinen Antti, Liukas Antti, Mäkelä Keijo T
a Department of Orthopaedics and Traumatology , Turku University Hospital , Turku.
b Pihlajalinna Ltd , Helsinki.
Acta Orthop. 2016 Dec;87(6):554-559. doi: 10.1080/17453674.2016.1246316. Epub 2016 Oct 19.
Background and purpose - In a previous registry report, short-term implant survival of hip resurfacing arthroplasty (HRA) in Finland was found to be comparable to that of total hip arthroplasty (THA). Since then, it has become evident that adverse reactions to metal debris (ARMDs) may also be associated with HRA, not only with large-diameter head metal-on-metal THA. The aim of the study was to assess medium- to long-term survivorship of HRA based on the Finnish Arthroplasty Register (FAR). Patients and methods - 5,068 HRAs performed during the period 2001-2013 in Finland were included. Kaplan-Meier survival analysis was used to calculate survival probabilities and their 95% confidence intervals (CIs). Cox multiple regression, with adjustment for age, sex, diagnosis, femoral head size, and hospital volume was used to analyze implant survival of HRA devices with revision for any reason as endpoint. The reference group consisted of 6,485 uncemented Vision/Bimetric and ABG II THAs performed in Finland over the same time period. Results - The 8-year survival, with any revision as an endpoint, was 93% (CI: 92-94) for Birmingham Hip Resurfacing (BHR), 86% (CI: 78-94) for Corin, 91% (CI: 89-94) for ReCap, 92% (CI: 89-96) for Durom, and was 72% (CI: 69-76) for the Articular Surface Replacement (ASR). The 10-year survival, with any revision as an endpoint, for reference THAs was 92% (CI: 91-92) and for all HRAs it was 86% (CI: 84-87%). Female HRA patients had about twice the revision risk of male patients. ASR had an inferior outcome: the revision risk was 4-fold higher than for BHR, the reference implant. Interpretation - The 10-year implant survival of HRAs is 86% in Finland. According to new recommendations from NICE (The National Institute for Health and Care Excellence), an HRA/THA should have a revision rate of 5% or less at 10 years. None of the HRAs studied achieved this goal.
背景与目的——在之前的登记报告中,发现芬兰髋关节表面置换术(HRA)的短期植入物存活率与全髋关节置换术(THA)相当。从那时起,很明显对金属碎屑的不良反应(ARMDs)可能也与HRA有关,而不仅仅与大直径股骨头金属对金属THA有关。本研究的目的是基于芬兰关节置换登记处(FAR)评估HRA的中长期生存率。
患者与方法——纳入了2001年至2013年期间在芬兰进行的5068例HRA。采用Kaplan-Meier生存分析来计算生存概率及其95%置信区间(CIs)。以任何原因翻修为终点,采用Cox多元回归分析,并对年龄、性别、诊断、股骨头大小和医院规模进行调整,以分析HRA装置的植入物存活率。对照组由同期在芬兰进行的6485例非骨水泥型Vision/Bimetric和ABG II THA组成。
结果——以任何翻修为终点,伯明翰髋关节表面置换术(BHR)的8年生存率为93%(CI:92-94),Corin为86%(CI:78-94),ReCap为91%(CI:89-94),Durom为92%(CI:89-96),关节表面置换术(ASR)为72%(CI:69-76)。以任何翻修为终点,对照组THA的10年生存率为92%(CI:91-92),所有HRA的10年生存率为86%(CI:84-87%)。女性HRA患者的翻修风险约为男性患者的两倍。ASR的结果较差:翻修风险比参考植入物BHR高4倍。
解读——在芬兰,HRA的10年植入物存活率为86%。根据英国国家卫生与临床优化研究所(NICE)的新建议,HRA/THA在10年时的翻修率应在5%或以下。所研究的HRA均未达到这一目标。