Volaklis Konstantinos, Mamadjanov Temur, Meisinger Christa, Linseisen Jacob
Lehrstuhl für Epidemiologie, LMU München am UNIKA-T, Neusaesser Str. 47, 86156, Augsburg, Germany.
Wien Klin Wochenschr. 2019 Jun;131(11-12):255-264. doi: 10.1007/s00508-019-1491-8. Epub 2019 Apr 8.
There is increasing evidence for an association between low muscular strength and depressive symptoms. In this review the existing literature on the association between muscular strength and depression particularly in older people as reported in epidemiological studies is summarized. From the literature search, conducted in PubMed (January 1980-May 2018), 17 papers (8 cross-sectional and 9 longitudinal studies) were selected. All cross-sectional studies reported significantly lower odds of having depressive symptoms with increased levels of muscular strength and this association persisted even after adjusting for several confounders including the level of physical activity. The majority of the longitudinal studies also reported that low muscular strength was independently associated with a higher risk of developing depression but more studies are needed to confirm this evidence. Furthermore, future investigations are needed to explore the exact mechanisms of muscular strength in relation to depression. Low muscular strength is a modifiable factor for depression, which is of great public health interest.
越来越多的证据表明，肌肉力量低下与抑郁症状之间存在关联。在这篇综述中，总结了流行病学研究中报道的关于肌肉力量与抑郁，特别是老年人抑郁之间关联的现有文献。通过在PubMed（1980年1月至2018年5月）中进行文献检索，选取了17篇论文（8篇横断面研究和9篇纵向研究）。所有横断面研究均报告，随着肌肉力量水平的提高，出现抑郁症状的几率显著降低，即使在调整了包括身体活动水平在内的多个混杂因素后，这种关联依然存在。大多数纵向研究也报告称，低肌肉力量与患抑郁症的较高风险独立相关，但需要更多研究来证实这一证据。此外，未来需要进行调查，以探索肌肉力量与抑郁相关的确切机制。低肌肉力量是抑郁症的一个可改变因素，这具有重大的公共卫生意义。
