中国大学一年级女生肌肉力量与抑郁症状之间的关联：一项横断面研究。
Association between muscle strength and depressive symptoms among Chinese female college freshmen: a cross-sectional study.
作者信息
Ren Zhongyu, Cao Jianhua, Li Yingke, Cheng Peng, Cao Bing, Hao Zongji, Yao Hui, Shi Dongzhe, Liu Bin, Chen Chang, Yang Guang, Peng Li, Guo Liya
机构信息
College of Physical Education and Key Laboratory of Physical Fitness Evaluation & Motor Function Monitoring, General Administration of Sport of China, Institute of Sports Science, Southwest University, Chongqing, 400715, China.
College of Physical Education, Chongqing Nursing Vocational College, Chongqing, 402763, China.
出版信息
BMC Musculoskelet Disord. 2020 Jul 31;21(1):510. doi: 10.1186/s12891-020-03478-w.
BACKGROUND
Increased physical activity level is related to lower risk of depressive symptoms, and there is an inverse association between muscle strength and risk of depressive symptoms among the elderly. Although there is evidence of an inverse association between muscle strength and depressive symptoms, the relationship between these variables in a younger population is still unknown. This study aimed to examine the association between handgrip strength, a representative indicator of skeletal muscle strength, and the risk of depressive symptoms among Chinese female college freshmen.
METHODS
A cross-sectional study was conducted among 867 participants aged between 16 and 23 years. Handgrip strength was measured with a handheld digital Smedley dynamometer, and handgrip strength relative to body weight (kg/kg) was calculated and was classified into tertiles as follows: low (0.32-0.50), medium (0.51-0.58), and high (0.59-0.94). Depressive symptoms were evaluated using the 20-item Zung self-rating depression scale (SDS), and three cutoff points were used to indicate different depression levels.
RESULTS
We found that 10.7% of participants were classified as having severe depressive symptoms using an SDS score of 50 as the cutoff point. After adjusting for potential confounders, the adjusted odds ratios and 95% confidence intervals (CIs) for moderate-to-severe depressive symptoms across tertiles of the relative handgrip strength were 1.00 (reference) for tertile 1, 0.614 (0.353, 1.069) for tertile 2, and 0.537 (0.292, 0.988) for tertile 3 (P for trend = 0.041). The significant associations remained when other cutoff points (SDS scores: 48 or 45) were used. Interactions between handgrip strength and potential confounders for depressive symptoms in the final models were not significant.
CONCLUSIONS
Our findings indicate that handgrip strength is inversely and independently related to the risk of depressive symptoms among Chinese female college freshmen. The present findings can help develop an effective intervention strategy against depression. Further intervention studies are needed to explore the mechanisms underlying the effects of handgrip strength on depressive symptoms.
背景
身体活动水平的提高与抑郁症状风险降低相关，并且老年人的肌肉力量与抑郁症状风险之间存在负相关。尽管有证据表明肌肉力量与抑郁症状之间存在负相关，但这些变量在年轻人群中的关系仍不清楚。本研究旨在探讨握力（骨骼肌力量的代表性指标）与中国大学新生女性抑郁症状风险之间的关联。
方法
对867名年龄在16至23岁之间的参与者进行了一项横断面研究。使用手持式数字斯梅德利测力计测量握力，并计算相对于体重（kg/kg）的握力，并将其分为三分位数，如下：低（0.32 - 0.50）、中（0.51 - 0.58）和高（0.59 - 0.94）。使用20项zung自评抑郁量表（SDS）评估抑郁症状，并使用三个临界点来表示不同的抑郁水平。
结果
我们发现，以SDS评分为50作为临界点，10.7%的参与者被归类为有严重抑郁症状。在调整潜在混杂因素后，相对握力三分位数中重度抑郁症状的调整优势比和95%置信区间（CI），第一三分位数为1.00（参考值），第二三分位数为0.614（0.353，1.069），第三三分位数为0.537（0.292，0.988）（趋势P = 0.041）。当使用其他临界点（SDS评分：48或45）时，显著关联仍然存在。最终模型中握力与抑郁症状潜在混杂因素之间的交互作用不显著。
结论
我们的研究结果表明，握力与中国大学新生女性抑郁症状风险呈负相关且独立相关。目前的研究结果有助于制定有效的抑郁症干预策略。需要进一步的干预研究来探索握力对抑郁症状影响的潜在机制。
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