Alharbi Mana
Department of Dermatology, Imam Muhammad ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
J Cosmet Dermatol. 2019 Oct;18(5):1202-1205. doi: 10.1111/jocd.12932. Epub 2019 Apr 9.
This review is primarily focusing on the legitimate concern about bacterial contamination after reuse of stored filling syringes and its associated risk of infections.
A comprehensive literature review was done through searching the PubMed, Medline, Google Scholar, and ResearchGate without setting a time limit. The following search terms were used soft tissue filler, hyaluronic acid, or calcium hydroxylapatite AND sterility, safety, retouch, touch up, or reuse.
Immediate replacing needles used in injection with a sterile substitute before storage was associated with no growth in one study (Archives of Facial Plastic Surgery, 11, 2009, 271) and growth in another study (Dermatologic Surgery, 2017, 43, 967). There was no reported infection in the only patient-based study that examined the adverse events among patients injected with stored hyaluronic acid filler syringes.
All published research showed that stored fillers are safe and do not increase the risk of biofilm formation.
本综述主要关注储存后的填充注射器重复使用后细菌污染的合理担忧及其相关的感染风险。
通过搜索PubMed、Medline、谷歌学术和ResearchGate进行全面的文献综述，不设时间限制。使用了以下搜索词：软组织填充剂、透明质酸或羟基磷灰石以及无菌、安全性、补妆、修饰或重复使用。
在一项研究中（《面部整形外科学档案》，11，2009，271），储存前立即用无菌替代品更换注射用针头与无细菌生长相关，而在另一项研究中（《皮肤外科手术》，2017，43，967）则有细菌生长。在唯一一项基于患者的研究中，对注射储存的透明质酸填充注射器的患者进行不良事件检查，未报告感染情况。
所有已发表的研究表明，储存的填充剂是安全的，不会增加生物膜形成的风险。
