Özdemir Ü, Türkyilmaz M A, Sayi O, Erpek S H, Nicholas R A J
Rev Sci Tech. 2018 Dec;37(3):831-836. doi: 10.20506/rst.37.3.2889.
Contagious caprine pleuropneumonia (CCPP) was detected for the first time on the European continent in the Thrace region of Turkey in 2002 following outbreaks of an unusually severe respiratory disease in goats. Mycoplasma capricolums ubspecies capripneumoniae (Mccp), the causative agent, was identified in many infected herds throughout the region by serological, bacteriological and molecular biological techniques. However, as no quantitative data on the prevalence and distribution of the disease have been gathered in the intervening years, the extent of infection is unknown. Consequently, in 2014, a random sample of 2,400 goats was drawn from a population of over 167,000 goats in the region by multistage sampling. Serum samples were collected and tested by a monoclonal antibodybased competitive enzyme-linked immunosorbent assay (cELISA). The overall prevalence of CCPP in Thrace was found to be just over 8%. The prevalence in the individual provinces was approximately 18%, 7%, 8% and 6% for Çanakkale, Edirne, K?rklareli and Tekirda?, respectively, while Istanbul province appeared to be CCPP-free. The results showed that CCPP has spread throughout the region and has become endemic, and may pose a potential risk to the neighbouring countries of Greece and Bulgaria. Mccp was regularly detected from lung samples of suspect goats until 2015 but since then there has been no further detection from clinical samples.
2002年，在土耳其色雷斯地区的山羊群中爆发了一种异常严重的呼吸道疾病后，欧洲大陆首次检测到山羊传染性胸膜肺炎（CCPP）。通过血清学、细菌学和分子生物学技术，在该地区许多受感染的畜群中鉴定出了病原体——山羊支原体山羊肺炎亚种（Mccp）。然而，在这期间没有收集到关于该疾病流行率和分布的定量数据，因此感染程度尚不清楚。因此，2014年，通过多阶段抽样从该地区超过16.7万只山羊的种群中随机抽取了2400只山羊样本。采集血清样本并通过基于单克隆抗体的竞争酶联免疫吸附测定（cELISA）进行检测。结果发现，色雷斯地区CCPP的总体流行率略高于8%。恰纳卡莱、埃迪尔内、克尔克拉雷利和泰基尔达省的个体省份流行率分别约为18%、7%、8%和6%，而伊斯坦布尔省似乎没有CCPP。结果表明，CCPP已在整个地区传播并成为地方病，可能对邻国希腊和保加利亚构成潜在风险。直到2015年，仍定期从疑似山羊的肺部样本中检测到Mccp，但从那以后，临床样本中再也没有检测到。
