Liu Wei, Zhong Dayou, Yu Cheng-Long, Zhang Yan, Wu Di, Feng Ya-Lan, Cong Hengjiang, Lu Xiuqiang, Liu Wen-Bo
Engineering Research Center of Organosilicon Compounds & Materials, Ministry of Education, College of Chemistry and Molecular Sciences , Wuhan University . 299 Bayi Road , Wuhan , Hubei 430072 , China.
Fuqing Branch of Fujian Normal University , Fuzhou , Fujian 350300 , China.
Org Lett. 2019 Apr 19;21(8):2673-2678. doi: 10.1021/acs.orglett.9b00660. Epub 2019 Apr 9.
It is challenging to develop simple and low cost catalytic systems while maintaining high reactivity and selectivity. An iron-catalyzed intramolecular C-H amination of sulfamate esters using simple and cheap ligands is reported with general substrate scope (31 examples, up to 95% yield). The addition of second ligand, bipyridine, is able to accelerate the reaction and increase the yield. The ready availability of these iron catalysts provides a promising approach to selective introduction of nitrogen into hydrocarbon feedstock.
在保持高反应活性和选择性的同时开发简单且低成本的催化体系具有挑战性。本文报道了一种铁催化的使用简单廉价配体的氨基磺酸酯分子内C-H胺化反应，具有广泛的底物范围（31个例子，产率高达95%）。添加第二种配体联吡啶能够加速反应并提高产率。这些铁催化剂的 readily availability 为将氮选择性引入烃类原料提供了一种有前景的方法。 （注：原文中“readily availability”表述有误，可能是“ready availability”，翻译为“容易获得” ）
