School of Science and Health, Western Sydney University, Locked Bag1797, Penrith, NSW 2571, Australia.
School of Social Sciences and Psychology, Western Sydney University, Locked Bag1797, Penrith, NSW 2751, Australia.
Int J Environ Res Public Health. 2019 Apr 8;16(7):1241. doi: 10.3390/ijerph16071241.
Child mortality in Nepal has reduced, but the rate is still above the Sustainable Development Goal target of 20 deaths per 1000 live births. This study aimed to identify common factors associated with under-five mortality in Nepal. Survival information of 16,802 most recent singleton live births from the Nepal Demographic and Health Survey for the period (2001⁻2016) were utilized. Survey-based Cox proportional hazard models were used to examine factors associated with under-five mortality. Multivariable analyses revealed the most common factors associated with mortality across all age subgroups included: mothers who reported previous death of a child [adjusted hazard ratio (aHR) 17.33, 95% confidence interval (CI) 11.44, 26.26 for neonatal; aHR 13.05, 95% CI 7.19, 23.67 for post-neonatal; aHR 15.90, 95% CI 11.38, 22.22 for infant; aHR 16.98, 95% CI 6.19, 46.58 for child; and aHR 15.97, 95% CI 11.64, 21.92 for under-five mortality]; nonuse of tetanus toxoids (TT) vaccinations during pregnancy (aHR 2.28, 95% CI 1.68, 3.09 for neonatal; aHR 1.86, 95% CI 1.24, 2.79 for post-neonatal; aHR 2.44, 95% CI 1.89, 3.15 for infant; aHR 2.93, 95% CI 1.51, 5.69 for child; and aHR 2.39, 95% CI 1.89, 3.01 for under-five mortality); and nonuse of contraceptives among mothers (aHR 1.69, 95% CI 1.21, 2.37 for neonatal; aHR 2.69, 95% CI 1.67, 4.32 for post-neonatal; aHR 2.01, 95% CI 1.53, 2.64 for infant; aHR 2.47, 95% CI 1.30, 4.71 for child; and aHR 2.03, 95% CI 1.57, 2.62 for under-five mortality). Family planning intervention as well as promotion of universal coverage of at least two doses of TT vaccine are essential to help achieve child survival Sustainable Development Goal (SDG) targets of <20 under-five deaths and <12 neonatal deaths per 1000 births by the year 2030.
尼泊尔的儿童死亡率有所下降,但仍高于可持续发展目标规定的每千名活产儿 20 例死亡的目标。本研究旨在确定与尼泊尔五岁以下儿童死亡相关的常见因素。利用尼泊尔人口与健康调查(2001-2016 年)期间最近的 16802 名单胎活产儿的生存信息。采用基于调查的 Cox 比例风险模型来研究与五岁以下儿童死亡相关的因素。多变量分析显示,所有年龄组中最常见的与死亡相关的因素包括:报告以前有孩子死亡的母亲[新生儿的调整后危险比(aHR)为 17.33,95%置信区间(CI)为 11.44,26.26;新生儿后为 13.05,95%CI 为 7.19,23.67;婴儿为 15.90,95%CI 为 11.38,22.22;儿童为 16.98,95%CI 为 6.19,46.58;五岁以下儿童为 15.97,95%CI 为 11.64,21.92];母亲在怀孕期间未使用破伤风类毒素(TT)疫苗(新生儿 aHR 为 2.28,95%CI 为 1.68,3.09;新生儿后 aHR 为 1.86,95%CI 为 1.24,2.79;婴儿 aHR 为 2.44,95%CI 为 1.89,3.15;儿童 aHR 为 2.93,95%CI 为 1.51,5.69;五岁以下儿童 aHR 为 2.39,95%CI 为 1.89,3.01);母亲未使用避孕药具(新生儿 aHR 为 1.69,95%CI 为 1.21,2.37;新生儿后 aHR 为 2.69,95%CI 为 1.67,4.32;婴儿 aHR 为 2.01,95%CI 为 1.53,2.64;儿童 aHR 为 2.47,95%CI 为 1.30,4.71;五岁以下儿童 aHR 为 2.03,95%CI 为 1.57,2.62)。计划生育干预以及促进至少两剂 TT 疫苗的普遍覆盖,对于帮助实现到 2030 年儿童生存可持续发展目标(SDG)中<20 例五岁以下儿童死亡和<12 例新生儿死亡的目标至关重要。