Department of Clinical Science/Ophthalmology, Umeå University, Umeå, Sweden.
Epidemiology and Global Health Unit, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
J Cataract Refract Surg. 2019 Jun;45(6):803-809. doi: 10.1016/j.jcrs.2018.12.023. Epub 2019 Apr 6.
To study the impact of corneal guttata on postoperative visual acuity and patients' self-assessed visual function after cataract surgery.
Patient data from 49 Swedish cataract surgery units.
Retrospective cross-sectional register-based study.
Data from patients who had cataract surgery from 2010 to 2017 and completed the Catquest-9SF questionnaire were obtained from the Swedish National Cataract Register. Logistic proportional odds regression was used to model the impact of corneal guttata on the visual acuity and self-assessed visual function. Adjustments were made for age, sex, ocular comorbidities, days to follow-up, preoperative corrected distance visual acuity (CDVA) and preoperative Rasch person score. The main outcome measures were postoperative CDVA and Rasch person score calculated from the Catquest-9SF questionnaire.
The study comprised data from 33 741 patients. Cataract surgery greatly improved CDVA and self-assessed visual function in patients both with and without corneal guttata. Still, corneal guttata was significantly associated with a poorer visual acuity and a worse self-assessed visual function after cataract surgery. The negative effect of corneal guttata on visual acuity was most prominent during the first 3 weeks postoperatively, but it persisted at least 3 months postoperatively.
Patients with corneal guttata benefit substantially from cataract surgery but have an additional risk for inferior results compared with patients without corneal guttata. These findings could serve as valuable tools in clinical practice, in particular, when deciding to perform cataract surgery and how to inform the patient about surgical benefits and risks.
研究白内障术后角膜后弹力层小滴对术后视力和患者自评视觉功能的影响。
本研究基于瑞典 49 家白内障手术中心的数据。
回顾性、基于人群的注册研究。
本研究纳入了 2010 年至 2017 年间在瑞典全国白内障登记处完成白内障手术且填写了 Catquest-9SF 问卷的患者数据。采用逻辑比例优势回归模型分析角膜后弹力层小滴对视力和自评视觉功能的影响。调整了年龄、性别、眼部合并症、随访天数、术前矫正远视力(CDVA)和术前 Rasch 个人评分等因素。主要观察指标为术后 CDVA 和 Catquest-9SF 问卷得出的 Rasch 个人评分。
共纳入 33741 例患者的数据。白内障手术能明显改善有或无角膜后弹力层小滴的患者的 CDVA 和自评视觉功能。然而,角膜后弹力层小滴与白内障术后视力和自评视觉功能更差显著相关。角膜后弹力层小滴对视力的负面影响在术后 3 周内最为显著,但至少在术后 3 个月仍存在。
尽管白内障术后角膜后弹力层小滴患者的获益明显,但与无角膜后弹力层小滴患者相比,他们的结果仍存在额外风险。这些发现可为临床实践提供有价值的工具,特别是在决定是否进行白内障手术以及如何向患者告知手术获益和风险时。