McIntyre G, Stanford J L
Eur J Respir Dis. 1986 Sep;69(3):135-41.
Twenty Mycobacterium avium/intracellulare strains of diverse origins and two reference strains of each of Schaefer's serotypes 1-21 were examined by immunodiffusion analysis. The results produced three distinct groups, which we have called A, B and C. Two of these, A and B, appear to be variants, perhaps subspecies of M. avium, and Group C is M. intracellulare. Within each group, rough variants, untypable by Schaefer's agglutination method, were found to be antigenically identical to the smooth parent strain by immunodiffusion analysis. The results obtained were essentially in agreement with those of some previous workers based on animal pathogenicity studies, skin-test studies in sensitized guinea-pigs and DNA homology.
采用免疫扩散分析法检测了20株来源各异的鸟分枝杆菌/胞内分枝杆菌菌株以及 Schaefer 血清型1 - 21中每种血清型的2种参考菌株。结果产生了三个不同的组，我们将其称为A、B和C组。其中两组，即A组和B组，似乎是变种，可能是鸟分枝杆菌的亚种，而C组是胞内分枝杆菌。在每个组内，通过免疫扩散分析发现，用Schaefer凝集法无法分型的粗糙变种在抗原性上与光滑亲本菌株相同。所获得的结果与一些先前研究人员基于动物致病性研究、致敏豚鼠皮肤试验研究和DNA同源性得出的结果基本一致。
