Miyasaka Jordan Da Silva, Vieira Raphael V Gonzaga, Novalo-Goto Elaine Shizue, Montagna Erik, Wajnsztejn Rubens
Faculdade de Medicina do ABC, Santo André SP, Brasil.
Arq Neuropsiquiatr. 2019 Mar;77(3):194-207. doi: 10.1590/0004-282X20190014.
Scotopic sensitivity syndrome, later called Meares-Irlen syndrome or simply Irlen syndrome (IS) has been described as symptoms of poor reading ability due to poor color matching and distorted graphic images. Individuals with this syndrome are considered slow, ineffective readers with low comprehension and visual fatigue. It is still uncertain whether the disease pathophysiology is an independent entity or part of the dyslexia spectrum. Nevertheless, treatments with lenses and colored filters have been proposed to alleviate the effect of the luminous contrast and improve patients' reading performance. However, no evidence of treatment effectiveness has been achieved.
The aim of the present study was to obtain evidence about IS etiology, diagnosis and intervention efficacy.
A systematic review was performed covering the available studies on IS, assessing the available data according to their level of evidence, focusing on diagnostic tools, proposed interventions and related outcomes.
The data showed high heterogeneity among studies, and lack of evidence on the existence of IS and treatment effectiveness.
The syndrome as described, as well as its treatments, require further strong evidence.
暗适应敏感性综合征，后来被称为米尔斯-厄伦综合征或简称为厄伦综合征（IS），被描述为由于颜色匹配不佳和图形图像扭曲而导致阅读能力差的症状。患有这种综合征的人被认为是阅读速度慢、效率低、理解能力差且有视觉疲劳的读者。该疾病的病理生理学是一个独立的实体还是诵读困难谱系的一部分仍不确定。然而，有人提出使用镜片和彩色滤光片进行治疗，以减轻亮度对比度的影响并提高患者的阅读表现。然而，尚未获得治疗有效性的证据。
本研究的目的是获取有关IS病因、诊断和干预效果的证据。
进行了一项系统综述，涵盖了关于IS的现有研究，根据证据水平评估现有数据，重点关注诊断工具、提出的干预措施和相关结果。
数据显示研究之间存在高度异质性，并且缺乏关于IS存在和治疗有效性的证据。
所描述的综合征及其治疗方法需要进一步的确凿证据。
