Madrona Marcos Fatima, Panisello Royo Josefa M, Tarraga Marcos M Loreto, Rosich Nuria, Carbayo Herencia Julio A, Alins Josep, Castell Eudald, Tárraga López Pedro J
EAP Zona 5 A, Albacete, España.
Fufosa, Barcelona, España.
Clin Investig Arterioscler. 2019 Nov-Dec;31(6):245-250. doi: 10.1016/j.arteri.2019.02.002. Epub 2019 Apr 7.
To assess the effect of a motivated physical activity program on the lipid parameters most related to excess weight (triglycerides [TG], and high density lipoprotein cholesterol [HDL]) in a weight-loss intervention in obese and overweight patients.
A randomised and controlled, 2-arm, clinical trial and a 12-months follow-up was conducted. The patients included in the study were randomised into 2 intervention groups: Motivational intervention of obesity with a previously trained nurse (G1), motivational group, with digital platform support and motivated physical activity program (iwopi [G2]). The anthropometric variables measured were height, weight, Body Mass Index (BMI), as well as the analytical variables, total cholesterol, TG and HDL-C.
A total of 123 patients participated in the study, of which 61 were randomised to G1, and 62 to G2. Both groups significantly decreased weight at the end of the study, with the decrease in G1 being 4.898kg, and 6.292kg in G2. In both groups there was also a significantly decrease (P<.05) in total cholesterol and TG, and increase in HDL cholesterol, with these changes being more intense in the G2 group, as well as being the group that lost more weight.
Weight reduction is accompanied by favourable changes in lipid parameters related to overweight and obesity, being more intense the greater the weight loss.
在肥胖和超重患者的减肥干预中,评估一项有动机的体育活动计划对与超重最相关的血脂参数(甘油三酯[TG]和高密度脂蛋白胆固醇[HDL])的影响。
进行了一项随机对照的双臂临床试验,并进行了12个月的随访。纳入研究的患者被随机分为2个干预组:由一名经过预先培训的护士进行的肥胖动机干预(G1),即动机组,采用数字平台支持并有动机的体育活动计划(iwopi[G2])。测量的人体测量变量包括身高、体重、体重指数(BMI),以及分析变量、总胆固醇、TG和HDL-C。
共有123名患者参与了该研究,其中61名被随机分配到G1组,62名被随机分配到G2组。在研究结束时,两组的体重均显著下降,G1组下降了4.898kg,G2组下降了6.292kg。两组的总胆固醇和TG也显著下降(P<0.05),HDL胆固醇升高,G2组的这些变化更为明显,且该组体重减轻更多。
体重减轻伴随着与超重和肥胖相关的血脂参数的有利变化,体重减轻越多,变化越明显。