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青少年和成年早期狂饮与高血压的关联:来自全国青少年至成年健康纵向研究(1994-2008 年)的结果。

Association of binge drinking in adolescence and early adulthood with high blood pressure: findings from the National Longitudinal Study of Adolescent to Adult Health (1994-2008).

机构信息

Brown School at Washington University in St. Louis, St. Louis, Missouri, United States.

Division of General Medical Sciences, Washington University School of Medicine, St. Louis, Missouri, United States.

出版信息

J Epidemiol Community Health. 2019 Jul;73(7):652-659. doi: 10.1136/jech-2018-211594. Epub 2019 Apr 10.

Abstract

BACKGROUND

An investigation of the risk of high blood pressure (HBP) associated with heavy alcohol consumption in adolescence and early adulthood is lacking. Therefore, we aimed to investigate the association between binge drinking from adolescence to early adulthood and the risk of HBP in early adulthood.

METHODS

We applied logistic regression to publicly available, population-representative data from waves I (1994-1995; ages 12-18) and IV (2007-2008; ages 24-32) of the National Longitudinal Study of Adolescent to Adult Health (n=5114) to determine whether past 12-month binge drinking in adolescence (wave I) and early adulthood (wave IV) was associated with HBP in early adulthood after adjusting for covariates, including smoking and body mass index. HBP was defined according to both the former and new classifications.

RESULTS

HBP was significantly, positively associated with infrequent binge drinking (less than once a week) in adolescence based on the new classification (overall: OR 1.23, 95% CI 1.02 to 1.49; male: OR 1.35, 95% CI 1.00 to 1.81) and frequent binge drinking (heavy consumption) in adolescence based on the former classification (overall: OR= 1.64, 95% CI 1.22 to 2.22; male: OR= 1.79, 95% CI 1.23 to 2.60). The risk of HBP was high when participants engaged in frequent binge drinking in both adolescence and early adulthood, especially based on the former classification (overall: OR 2.43, 95% CI 1.13 to 5.20; female: OR 5.81, 95% CI 2.26 to 14.93).

CONCLUSION

Binge drinking in adolescence may increase risk of HBP in early adulthood. This association is independent of other important risk factors for HPB, such as smoking and obesity.

摘要

背景

目前缺乏青少年期和成年早期大量饮酒与高血压(HBP)风险相关的研究。因此,我们旨在调查青少年期到成年早期的 binge drinking 与成年早期 HBP 风险之间的关联。

方法

我们应用逻辑回归分析了全国青少年至成人健康纵向研究(NLAHS)I 期(1994-1995 年;年龄 12-18 岁)和 IV 期(2007-2008 年;年龄 24-32 岁)中公开的、具有代表性的人群数据,以确定青少年期(I 期)和成年早期(IV 期)过去 12 个月的 binge drinking 是否与成年早期的 HBP 相关,调整了包括吸烟和体重指数在内的混杂因素。根据以前和新的分类标准定义 HBP。

结果

根据新的分类标准,青少年期非频繁 binge drinking(每周少于一次)显著增加了 HBP 的风险(总体:OR 1.23,95%CI 1.02-1.49;男性:OR 1.35,95%CI 1.00-1.81),而根据以前的分类标准,青少年期频繁 binge drinking(重度饮酒)增加了 HBP 的风险(总体:OR=1.64,95%CI 1.22-2.22;男性:OR=1.79,95%CI 1.23-2.60)。当参与者在青少年期和成年早期都有频繁 binge drinking 时,HBP 的风险很高,尤其是根据以前的分类标准(总体:OR 2.43,95%CI 1.13-5.20;女性:OR 5.81,95%CI 2.26-14.93)。

结论

青少年期 binge drinking 可能会增加成年早期 HBP 的风险。这种关联独立于 HBP 的其他重要风险因素,如吸烟和肥胖。

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