Schnauß Jörg, Händler Tina, Käs Josef A
Institute for Experimental Physics I, Universität Leipzig, Linnéstraße 5, Leipzig 04103, Germany.
Fraunhofer Institute for Cell Therapy and Immunology, Perlickstraße 1, Leipzig 04103, Germany.
Polymers (Basel). 2016 Jul 28;8(8):274. doi: 10.3390/polym8080274.
Bundles and networks of semiflexible biopolymers are key elements in cells, lending them mechanical integrity while also enabling dynamic functions. Networks have been the subject of many studies, revealing a variety of fundamental characteristics often determined via bulk measurements. Although bundles are equally important in biological systems, they have garnered much less scientific attention since they have to be probed on the mesoscopic scale. Here, we review theoretical as well as experimental approaches, which mainly employ the naturally occurring biopolymer actin, to highlight the principles behind these structures on the single bundle level.
半柔性生物聚合物束和网络是细胞中的关键元素，赋予细胞机械完整性的同时还能实现动态功能。网络一直是许多研究的主题，揭示了通常通过宏观测量确定的各种基本特征。尽管束在生物系统中同样重要，但由于必须在介观尺度上进行探测，它们受到的科学关注要少得多。在这里，我们回顾理论和实验方法，这些方法主要采用天然存在的生物聚合物肌动蛋白，以突出单束水平上这些结构背后的原理。
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