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大型关节骨软骨缺损的置换:绵羊实验模型

Replacement of osteochondral defect of large joints: An experimental model in sheep.

作者信息

Airapetov Georgii Alexandrovich, Iyalomhe Oshozimhede Emeghomhe, Adzege Faeren Matilda

机构信息

Department of Traumatology and Orthopedics, Stavropol State Medical University, Russia.

出版信息

J Orthop. 2019 Mar 25;16(4):308-311. doi: 10.1016/j.jor.2019.02.030. eCollection 2019 Jul-Aug.

DOI:10.1016/j.jor.2019.02.030
PMID:30976145
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6441705/
Abstract

AIM

To improve the treatment results of patients with osteochondral defects of large joints.

MATERIALS AND METHODS

A prospective study was conducted on 30 animals (60 knee joints) aged 1.5-3 years. All animals were divided into 3 groups of 10 each, depending on the method of replacement of the osteo-chondral defect.

RESULTS

6 months after intervention using the proposed method, a good prognosis can be given and good long-term results expected despite the full axial load on the joint a few hours after the operation.

摘要

目的

提高大关节骨软骨缺损患者的治疗效果。

材料与方法

对30只年龄在1.5至3岁的动物(60个膝关节)进行了一项前瞻性研究。根据骨软骨缺损的置换方法,将所有动物分为3组,每组10只。

结果

采用所提出的方法进行干预6个月后,尽管术后数小时关节就承受了完全的轴向负荷,但仍能给出良好的预后,并预期会有良好的长期效果。

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Acta Orthop Belg. 2014 Jun;80(2):251-9.
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Knee osteoarthritis: hyaluronic acid, platelet-rich plasma or both in association?膝骨关节炎:透明质酸、富血小板血浆还是两者联合使用?
Expert Opin Biol Ther. 2014 May;14(5):635-49. doi: 10.1517/14712598.2014.889677. Epub 2014 Feb 17.
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Microfracture technique versus osteochondral autologous transplantation mosaicplasty in patients with articular chondral lesions of the knee: a prospective randomized trial with long-term follow-up.微骨折技术与骨软骨自体移植马赛克成形术治疗膝关节关节软骨病变患者:一项具有长期随访的前瞻性随机试验。
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Arch Phys Med Rehabil. 2014 Mar;95(3):562-75. doi: 10.1016/j.apmr.2013.11.006. Epub 2013 Nov 27.
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Activity levels are higher after osteochondral autograft transfer mosaicplasty than after microfracture for articular cartilage defects of the knee: a retrospective comparative study.骨软骨马赛克移植成形术治疗膝关节软骨缺损后活动水平高于微骨折术:一项回顾性对比研究。
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Open Orthop J. 2011;5 Suppl 2:242-8. doi: 10.2174/1874325001105010242. Epub 2011 Jul 28.
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Int J Clin Exp Med. 2011;4(1):81-90. Epub 2011 Feb 10.
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