Motallebzadeh Nader, Jayaprakash Geetha, Mohammadi Elham
RR College of Pharmacy, Chikkabanavara, Bangalore, India.
Department of Pharmacy Practice, RR College of Pharmacy, Chikkabanavara, Bangalore, India.
Open Access Maced J Med Sci. 2019 Mar 28;7(6):987-991. doi: 10.3889/oamjms.2019.172. eCollection 2019 Mar 30.
Irrational prescribing for geriatric patients has become an important public health problem worldwide. Because India is one of the most populated countries having a great proportion of old people in the world, studies on the prevalence of inappropriate prescriptions can be very beneficial to increase the knowledge of health care providers and to reduce the occurrence of adverse drug events among this population.
A group of 482 inpatients above 64 years old were enrolled in a prospective study. Chart review method was used. The data were collected from patients' prescription and medicine charts. Each prescription was checked individually for the inappropriate drug by using the AGS 2015 Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults. Suggestions were given to the physicians for inappropriate medications.
The prevalence of potentially inappropriate medication is found to be 11.66% (n = 56). Out of 56 inappropriate medications, the most frequently inappropriate medication is Digoxin (25%) followed by Sprinolactone 19.64%. This study founds age, some medication, length of stay and number of diagnosis as predictors for getting a PIM. Feedback of the physicians varies based on the suggestions.
This study concludes that the prevalence of PIMs among geriatrics patients of ≥ 65 years old is 11.66%. Some predictors have been identified for getting a PIM. This study shows that physicians' feedback is dependent on the suggestions being given.
老年患者不合理用药已成为全球重要的公共卫生问题。由于印度是世界上人口最多且老年人比例很大的国家之一，关于不适当处方患病率的研究对于增加医疗保健提供者的知识以及减少该人群中药物不良事件的发生可能非常有益。
一组482名64岁以上的住院患者被纳入一项前瞻性研究。采用病历审查方法。数据从患者的处方和药历中收集。使用2015年更新的美国老年医学会（AGS）老年人潜在不适当用药的Beers标准，对每张处方单独检查是否存在不适当药物。针对不适当用药向医生提出了建议。
发现潜在不适当用药的患病率为11.66%（n = 56）。在56种不适当用药中，最常出现的不适当药物是地高辛（25%），其次是螺内酯（19.64%）。本研究发现年龄、某些药物、住院时间和诊断数量是获得潜在不适当用药的预测因素。医生的反馈因建议而异。
本研究得出结论，65岁及以上老年患者中潜在不适当用药的患病率为11.66%。已确定了一些获得潜在不适当用药的预测因素。本研究表明医生的反馈取决于所给出的建议。
