Robinson Heather A, Dam Rinita, Hassan Lamiece, Jenkins David, Buchan Iain, Sperrin Matthew
Farr Institute, University of Manchester, Vaughan House, Portsmouth St, Manchester, M13 9GB, UK.
Manchester Academic Health Science Centre, UK.
Prev Med Rep. 2019 Mar 12;14:100834. doi: 10.1016/j.pmedr.2019.100834. eCollection 2019 Jun.
Children's body mass index (BMI) growth trajectories are associated with adult health outcomes, and vary by geography and epoch. Understanding these trajectories could help to identify high risk children and thus support improved health outcomes. In this review, we compare and quantitatively analyse BMI level and trajectory data published since 2010. We characterise recent growth in children aged 4-11 years, an age range most frequently targeted for BMI intervention, yet less studied than young childhood or infancy. Through searches in OVID, we identified 54 relevant texts which describe either post-2000 summary BMI values by age and gender in cohorts with sample sizes of over 1000 children, or the results of latent class analyses of BMI trajectories within the 4-11 year age range. Population level median growth curves were projected and visualised as weighted means. These BMI curves, based on data from 729,692 children, can be visually clustered into 'high' and 'low' charting groups with extreme outlying values. Within populations, latent class analyses converge on 3-4 individual child trajectories, two of which predispose adult overweight. These growth pathways diverge early in childhood, yet are not effectively distinguished via isolated BMI measurements taken between 4 and 11 years, meaning some high risk children may currently be poorly identified.
儿童的身体质量指数（BMI）增长轨迹与成人健康结果相关，且因地域和时代而异。了解这些轨迹有助于识别高危儿童，从而改善健康结果。在本综述中，我们对2010年以来发表的BMI水平和轨迹数据进行比较和定量分析。我们描述了4至11岁儿童近期的生长情况，这一年龄段是BMI干预最常针对的范围，但与幼儿期或婴儿期相比研究较少。通过在OVID中检索，我们确定了54篇相关文献，这些文献描述了样本量超过1000名儿童的队列中按年龄和性别划分的2000年后BMI汇总值，或4至11岁年龄范围内BMI轨迹的潜在类别分析结果。预测了人群水平的中位数生长曲线，并将其可视化为加权均值。这些基于729,692名儿童数据的BMI曲线可在视觉上聚类为“高”和“低”图表组，并带有极端异常值。在人群中，潜在类别分析得出3至4种个体儿童轨迹，其中两种易导致成人超重。这些生长途径在儿童早期就出现分歧，但通过4至11岁期间单独的BMI测量无法有效区分，这意味着一些高危儿童目前可能未被很好地识别。
