Trihia Helen J
Department of Pathology, "Metaxas" Cancer Hospital, Piraeus, Greece.
Gastrointest Tumors. 2019 Feb;5(3-4):63-67. doi: 10.1159/000495178. Epub 2018 Dec 21.
In recent years, the synchronous occurrence of tumors of different histotypes arising in the same organ has been reported more frequently in the literature. The simultaneous development of adenocarcinoma and gastrointestinal stromal tumor (GIST) has been documented rarely.
The coexistence of primary gastric adenocarcinoma and GIST has been detected incidentally on gastric mucosa, serosa or occasionally intramurally, at surgery, or gastroscopy for other reasons. We present a case of a 79-year-old male patient who underwent surgery for an advanced gastric carcinoma, where multiple nodules of GIST were incidentally discovered during the work-up of his gastrectomy specimen.
GISTs range from small "low-risk" tumors to sarcomas. Small GISTs are found incidentally during unrelated surgery or autopsy. Multiple GISTs are extremely rare and usually associated with hereditary diseases.
In any case of gastrointestinal neoplasm, the surgeon and pathologist should be alert to perform a thorough investigation. Our case could provide further awareness and insight into the entity of concurrent tumors.
近年来，同一器官内出现不同组织学类型肿瘤的同步发生在文献中报道得更为频繁。腺癌与胃肠道间质瘤（GIST）同时发生的情况鲜有记载。
原发性胃腺癌与GIST的共存已在手术时或因其他原因进行胃镜检查时偶然发现于胃黏膜、浆膜或偶尔在壁内。我们报告一例79岁男性患者，因进展期胃癌接受手术，在其胃切除标本检查过程中偶然发现多个GIST结节。
GIST范围从小的“低风险”肿瘤到肉瘤。小的GIST在无关手术或尸检时偶然发现。多个GIST极其罕见，通常与遗传性疾病相关。
在任何胃肠道肿瘤病例中，外科医生和病理学家都应警惕进行全面检查。我们的病例可为并发肿瘤的实体提供进一步的认识和见解。
