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哥伦比亚加勒比地区肺动脉高压的患病率。

Prevalence of pulmonary arterial hypertension in the Colombian Caribbean.

作者信息

Miranda-Machado Pablo, Baños-Alvarez Ivan, Alvarez-Barrios Alvaro

机构信息

1 ALZAK Foundation, Cartagena, Colombia.

2 Universidad Nacional de Colombia, Bogotá, Colombia.

出版信息

Pulm Circ. 2019 Apr-Jun;9(2):2045894019847643. doi: 10.1177/2045894019847643.

DOI:10.1177/2045894019847643
PMID:30977433
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6540494/
Abstract

In Latin America, there are no specific data on the prevalence of pulmonary arterial hypertension (PAH). For this reason, the Registro Latinoamericano de Hipertensión Pulmonar (RELAHP) is under development. The aim of this study is to estimate the prevalence of PAH in the Colombian Caribbean in 2015 based on data from a private health insurance company (PHIC) with coverage in that region. All the Individual Service Delivery Registries (RIPS) of all ambulatory care centers that serve the population of the Colombian Caribbean region affiliated with a PHIC selected for this research were reviewed. All patients who had a diagnosis of pulmonary hypertension (PH) were included (International Classification Diseases 10-Revision [ICD-10 I270, I272, I278, and I279]). Subsequently, the information on electronic medical records was reviewed. To estimate the prevalence of PAH, the total population of the PHIC and population projections of Colombian Caribbean by Departamento Administrativo Nacional de Estadisticas (DANE) was used. We identified 27 patients with a confirmed diagnosis of PH and 18 patients with a confirmed diagnosis of PAH. Taking into account the total population affiliated to the Caribbean Regional of the PHIC selected for the study in September 2015, a PAH prevalence of approximately 28 cases per million inhabitants is estimated. The mean of age was 22 ± 21.4 years (14.8% children) and 17 (62.9%) were girls/women. The majority of patients presented with PAH (Group 1) (66.6%). The estimated number of cases of PH in Colombian Caribbean in 2015 is approximately 292 cases or 1 in 35,760. Epidemiological estimates of PAH in the Colombian Caribbean are compatible with the definition of orphan or rare diseases. The majority of patients are female.

摘要

在拉丁美洲,尚无关于肺动脉高压(PAH)患病率的具体数据。因此,拉丁美洲肺动脉高压登记处(RELAHP)正在筹建中。本研究的目的是根据一家在该地区提供保险服务的私立医疗保险公司(PHIC)的数据,估算2015年哥伦比亚加勒比地区PAH的患病率。对为本研究选定的隶属于一家PHIC、服务于哥伦比亚加勒比地区人群的所有门诊护理中心的所有个体服务提供登记处(RIPS)进行了审查。纳入所有诊断为肺动脉高压(PH)的患者(国际疾病分类第10版[ICD - 10 I270、I272、I278和I279])。随后,对电子病历信息进行了审查。为估算PAH的患病率,使用了PHIC的总人口以及国家行政统计局(DANE)对哥伦比亚加勒比地区的人口预测。我们确定了27例确诊为PH的患者和18例确诊为PAH的患者。考虑到2015年9月选定用于该研究的PHIC加勒比地区附属的总人口,估计PAH患病率约为每百万居民28例。平均年龄为22±21.4岁(14.8%为儿童),17例(62.9%)为女孩/女性。大多数患者表现为PAH(第1组)(66.6%)。2015年哥伦比亚加勒比地区PH病例估计数约为292例,即每35,760人中有1例。哥伦比亚加勒比地区PAH的流行病学估计与孤儿病或罕见病的定义相符。大多数患者为女性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f11c/6540494/da3996b9d658/10.1177_2045894019847643-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f11c/6540494/da3996b9d658/10.1177_2045894019847643-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f11c/6540494/da3996b9d658/10.1177_2045894019847643-fig1.jpg

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