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对一系列接受右心导管检查的患者的血液动力学特征进行分析。哥伦比亚麦德林中心的经验。

Hemodynamic profiles in a series of patients undergoing right heart catheterization. Experience in one center of Medellin, Colombia.

机构信息

Departamento de Cardiología, Universidad CES.

Departamento de Medicina Interna.

出版信息

Arch Cardiol Mex. 2022;92(1):53-59. doi: 10.24875/ACM.20000528.

DOI:10.24875/ACM.20000528
PMID:34987239
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8771025/
Abstract

OBJETIVO

El objetivo de este estudio fue caracterizar la clasificación hemodinámica de la hipertensión pulmonar en una serie de pacientes llevados a cateterismo cardíaco derecho.

MÉTODOS: Se realizó un estudio retrospectivo y se revisaron los registros de los cateterismos cardíacos derechos practicados en personas mayores de 18 años entre enero de 2017 y diciembre del 2018. Se excluyó a aquéllos con datos incompletos o no concluyentes y se definieron los perfiles hemodinámicos de acuerdo con el resultado de la presión en cuña y la resistencia vascular pulmonar.

RESULTADOS

Se incluyó a 92 sujetos de los cuales se descartó hipertensión pulmonar en 4. El 26.1% se clasificó como precapilar, 31.8% como poscapilar y 42% como combinada. No hubo diferencias entre los tres grupos en edad y sexo; las presiones pulmonares fueron más elevadas en el grupo de hipertensión pulmonar precapilar. Se encontró presión en cuña elevada en el 73.8% de los pacientes y el cateterismo derecho reclasificó al 35% de los pacientes en un grupo hemodinámico diferente al esperado. En la mayor parte de estos casos se sospechaba HP precapilar por el diagnóstico anterior al procedimiento, pero los perfiles hemodinámicos encontrados correspondieron a hipertensión poscapilar o combinada.

CONCLUSIÓN: El cateterismo cardíaco derecho es necesario para la clasificación hemodinámica de la hipertensión pulmonar, que es importante no sólo para el diagnóstico sino para evaluar la causa de la enfermedad.

OBJECTIVE

To characterize the hemodynamic classification of pulmonary hypertension in a series of patients undergoing to right cardiac catheterization.

METHODS

This is a retrospective study, we analyze the records of all right heart catheterizations performed between January 2017 and December 2018, all patient older than 18 years were included and those with incomplete or inconclusive data were excluded. We identify three hemodynamic profiles according to the result of right heart catheterization.

RESULTS

92 subjects were included and pulmonary hypertension was ruled out in 4 of them; 26.1% were classified as precapillary, 31.8% postcapillary and 42% as combined pulmonary hypertesion. There were no differences between the 3 groups in age or sex, pulmonary pressures were higher in the precapillary pulmonary hypertension group, right catheterization reclassified 35% of the patients in a hemodynamic group in a different from that expected. Precapillary PH was suspected in most of these cases, but the hemodynamic profiles found in cardiac catheterization corresponded to post-capillary or combined pulmonay hypertension.

CONCLUSION

Right heart catheterization is necessary for the hemodynamic classification of pulmonary hypertension, which is important not only for diagnosis but also for evaluating the etiology of the disease.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a65/8771025/f7edc355f3e0/ACM-92-53-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a65/8771025/a5d480a86ca3/ACM-92-53-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a65/8771025/f7edc355f3e0/ACM-92-53-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a65/8771025/a5d480a86ca3/ACM-92-53-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a65/8771025/f7edc355f3e0/ACM-92-53-g002.jpg
摘要

目的

本研究旨在对一系列接受右心导管术的患者的肺动脉高压血液动力学分类进行特征描述。

方法

进行回顾性研究,分析 2017 年 1 月至 2018 年 12 月期间年龄大于 18 岁的所有右心导管术患者的记录。排除数据不完整或不确定的患者,并根据楔压和肺血管阻力的结果定义血液动力学特征。

结果

共纳入 92 例患者,其中 4 例排除肺动脉高压。26.1%为毛细血管前型,31.8%为毛细血管后型,42%为混合型。三组间年龄和性别无差异;毛细血管前型肺动脉高压患者的肺动脉压较高。73.8%的患者出现楔压升高,右心导管术将 35%的患者重新分类到预期以外的血液动力学组。在这些病例中,大多数患者在术前诊断为毛细血管前肺动脉高压,但在右心导管术中发现的血液动力学特征与毛细血管后或混合性肺动脉高压相符。

结论

右心导管术对于肺动脉高压的血液动力学分类是必要的,这不仅对诊断很重要,而且对评估疾病的病因也很重要。

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本文引用的文献

1
Right Heart Catheterization-Related Complications: A Review of the Literature and Best Practices.右心导管术相关并发症:文献回顾与最佳实践。
Cardiol Rev. 2020 Jan/Feb;28(1):36-41. doi: 10.1097/CRD.0000000000000270.
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How to diagnose heart failure with preserved ejection fraction: the HFA-PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC).如何诊断射血分数保留的心力衰竭:HFA-PEFF 诊断算法:欧洲心脏病学会(ESC)心力衰竭协会(HFA)的共识推荐。
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哥伦比亚加勒比地区肺动脉高压的患病率。
Pulm Circ. 2019 Apr-Jun;9(2):2045894019847643. doi: 10.1177/2045894019847643.
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EXPRESS: Right Heart in Pulmonary Hypertension: From Adaptation to Failure.快报:肺动脉高压中的右心:从适应到衰竭
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Eur Respir J. 2019 Jan 24;53(1). doi: 10.1183/13993003.01908-2018. Print 2019 Jan.
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Pulmonary hypertension due to left heart disease.左心疾病所致肺动脉高压。
Eur Respir J. 2019 Jan 24;53(1). doi: 10.1183/13993003.01897-2018. Print 2019 Jan.
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Diagnosis of pulmonary hypertension.肺动脉高压的诊断。
Eur Respir J. 2019 Jan 24;53(1). doi: 10.1183/13993003.01904-2018. Print 2019 Jan.
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Haemodynamic definitions and updated clinical classification of pulmonary hypertension.血流动力学定义和肺动脉高压的最新临床分类。
Eur Respir J. 2019 Jan 24;53(1). doi: 10.1183/13993003.01913-2018. Print 2019 Jan.
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Echocardiographic assessment of pulmonary hypertension: a guideline protocol from the British Society of Echocardiography.肺动脉高压的超声心动图评估:英国超声心动图学会的指南方案
Echo Res Pract. 2018 Sep;5(3):G11-G24. doi: 10.1530/ERP-17-0071.
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