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[其他特定类型糖尿病与外分泌性胰腺功能不全(2019年更新)]

[Other specific types of diabetes and exocrine pancreatic insufficiency (Update 2019)].

作者信息

Kaser Susanne, Winhofer-Stöckl Yvonne, Kazemi-Shirazi Lili, Hofer Sabine E, Brath Helmut, Sourij Harald, Vila Greisa, Abrahamian Heidemarie, Riedl Michaela, Weitgasser Raimund, Resl Michael, Clodi Martin, Luger Anton

机构信息

Department für Innere Medizin I, Medizinische Universität Innsbruck, Anichstraße 35, 6020, Innsbruck, Österreich.

Christian Doppler Labor für Insulinresistenz, Medizinische Universität Innsbruck, Innsbruck, Österreich.

出版信息

Wien Klin Wochenschr. 2019 May;131(Suppl 1):16-26. doi: 10.1007/s00508-019-1454-0.

Abstract

The heterogenous catagory "specific types of diabetes due to other causes" encompasses disturbances in glucose metabolism due to other endocrine disorders such as acromegaly or hypercortisolism, drug-induced diabetes (e. g. antipsychotic medications, glucocorticoids, immunosuppressive agents, highly active antiretroviral therapy (HAART)), genetic forms of diabetes (e. g. Maturity Onset Diabetes of the Young (MODY), neonatal diabetes, Down Syndrome, Klinefelter Syndrome, Turner Syndrome), pancreatogenic diabetes (e. g. postoperatively, pancreatitis, pancreatic cancer, haemochromatosis, cystic fibrosis), and some rare autoimmune or infectious forms of diabetes. Diagnosis of specific diabetes types might influence therapeutic considerations. Exocrine pancreatic insufficiency is not only found in patients with pancreatogenic diabetes but is also frequently seen in type 1 and long-standing type 2 diabetes.

摘要

“其他原因所致特定类型糖尿病”这一异质性类别包括由其他内分泌疾病(如肢端肥大症或皮质醇增多症)、药物性糖尿病(如抗精神病药物、糖皮质激素、免疫抑制剂、高效抗逆转录病毒疗法(HAART))、遗传性糖尿病(如青年发病的成年型糖尿病(MODY)、新生儿糖尿病、唐氏综合征、克兰费尔特综合征、特纳综合征)、胰腺性糖尿病(如术后、胰腺炎、胰腺癌、血色素沉着症、囊性纤维化)以及一些罕见的自身免疫性或感染性糖尿病形式所导致的葡萄糖代谢紊乱。特定糖尿病类型的诊断可能会影响治疗考量。外分泌性胰腺功能不全不仅见于胰腺性糖尿病患者,在1型糖尿病和长期2型糖尿病患者中也很常见。

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