Department of Chemistry, Karaj Branch, Islamic Azad University, Karaj, Iran.
Mol Divers. 2020 May;24(2):463-476. doi: 10.1007/s11030-019-09947-2. Epub 2019 Apr 12.
MgCl has been reported to be a versatile reagent especially as a Lewis acid catalyst in a variety of organic transformations including the preparation of heterocyclic compounds, the protection of functional groups and condensation reaction. Also the use of MgCl in the preparation of metallic magnesium and the application of magnesium chloride in biochemistry such as anesthetic for cephalopods, the separation of serum high-density lipoprotein, effect of MgCl on rabbit bronchial smooth muscle, antimicrobial properties of magnesium chloride and effect of MgCl on the quality of life for patients with fibromyalgia have been reported. Therefore, in this article the use of MgCl in organic chemistry and biochemistry is reviewed. MgCl has been reported to be a versatile reagent especially as a Lewis acid catalyst in a variety of organic transformations including the preparation of heterocyclic compounds, the protection of functional groups and condensation reaction. Also the use of MgCl in the preparation of metallic magnesium and the application of magnesium chloride in biochemistry such as anesthetic for cephalopods, the separation of serum high-density lipoprotein, effect of MgCl on rabbit bronchial smooth muscle, antimicrobial properties of magnesium chloride and effect of MgCl on the quality of life for patients with fibromyalgia have been reported. Therefore, in this article the use of MgCl in organic chemistry and biochemistry is reviewed.
氯化镁已被报道是一种多功能试剂，特别是作为路易斯酸催化剂，在各种有机转化中包括杂环化合物的制备、官能团的保护和缩合反应。此外，氯化镁在制备金属镁中的应用以及氯化镁在生物化学中的应用，如头足类动物的麻醉剂、血清高密度脂蛋白的分离、氯化镁对兔支气管平滑肌的影响、氯化镁的抗菌性能以及氯化镁对纤维肌痛患者生活质量的影响也有报道。因此，本文综述了氯化镁在有机化学和生物化学中的应用。
