Carr R J, Bilton R F, Atkinson T
Appl Environ Microbiol. 1986 Nov;52(5):1112-6. doi: 10.1128/aem.52.5.1112-1116.1986.
The biochemical response of the microorganisms Lipomyces starkeyi (Lod & Rij), Escherichia coli K-12 W3110, Bacillus subtilis 168 (Marburg) and Pseudomonas sp. strain TTO1 to the presence of growth-inhibitory concentrations of paraquat was studied. Paraquat was added to each culture at a concentration previously determined to reduce the culture growth rate by up to 50%. The changes in activity of a number of enzymes previously shown to be associated with the defense of the mammalian system against the action of paraquat were studied. While the response of E. coli was in agreement with that found in other studies of this microorganism and supports a commonly accepted mechanism for paraquat toxicity, the results obtained with L. starkeyi, B. subtilis, and Pseudomonas sp. strain TTO1 suggest that other mechanisms exist for protection against the toxicity of paraquat.
研究了微生物斯达氏油脂酵母(Lod & Rij)、大肠杆菌K-12 W3110、枯草芽孢杆菌168(马尔堡)和假单胞菌属菌株TTO1对百草枯生长抑制浓度的生化反应。将百草枯以先前确定的浓度添加到每种培养物中,该浓度可使培养物生长速率降低高达50%。研究了先前显示与哺乳动物系统抵御百草枯作用相关的多种酶的活性变化。虽然大肠杆菌的反应与对该微生物的其他研究结果一致,并支持一种普遍接受的百草枯毒性机制,但用斯达氏油脂酵母、枯草芽孢杆菌和假单胞菌属菌株TTO1获得的结果表明,存在其他抵御百草枯毒性的机制。